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- NCIT_C165280 IAO_0000115 "A radioimmunoconjugate composed of the anti-CD38 monoclonal antibody (MoAb) OKT10-B10 labeled with the alpha-emitting radionuclide astatine (At) 211 (211At), with potential antineoplastic activity. Upon administration of astatine At 211 anti-CD38 MoAb OKT10-B10, the MoAb moiety targets and binds to CD38-expressing tumor cells, thereby delivering a cytotoxic dose of alpha radiation directly to the CD38-expressing tumor cells. CD38, a type II transmembrane glycoprotein and tumor-associated antigen (TAA), is present on various immune cells and in hematologic malignancies; its expression has been correlated with poor prognosis." @default.
- NCIT_C165280 NCIT_A32 NCIT_C1909 @default.
- NCIT_C165280 NCIT_A7 NCIT_C84323 @default.
- NCIT_C165280 NCIT_NHC0 "C165280" @default.
- NCIT_C165280 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C165280 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C165280 NCIT_P107 "Astatine At 211 Anti-CD38 Monoclonal Antibody OKT10-B10" @default.
- NCIT_C165280 NCIT_P108 "Astatine At 211 Anti-CD38 Monoclonal Antibody OKT10-B10" @default.
- NCIT_C165280 NCIT_P208 "CL978515" @default.
- NCIT_C165280 NCIT_P322 "CTRP" @default.
- NCIT_C165280 NCIT_P322 "GDC" @default.
- NCIT_C165280 NCIT_P329 "799762" @default.
- NCIT_C165280 NCIT_P330 "799762" @default.
- NCIT_C165280 NCIT_P375 "Astatine At 211 Anti-CD38 Monoclonal Antibody OKT10-B10" @default.
- NCIT_C165280 NCIT_P399 "799762" @default.
- NCIT_C165280 normalizedInformationContent "100" @default.
- NCIT_C165280 referenceCount "1" @default.
- NCIT_C165280 hasExactSynonym "211At-OKT10-B10" @default.
- NCIT_C165280 hasExactSynonym "Astatine 211-labeled Anti-CD38 Monoclonal Antibody OKT10-B10" @default.
- NCIT_C165280 hasExactSynonym "Astatine At 211 Anti-CD38 MoAb OKT10-B10" @default.
- NCIT_C165280 hasExactSynonym "Astatine At 211 Anti-CD38 Monoclonal Antibody OKT10-B10" @default.
- NCIT_C165280 hasExactSynonym "Astatine-211-OKT10-B10" @default.
- NCIT_C165280 hasExactSynonym "At211-OKT10-B10" @default.
- NCIT_C165280 hasExactSynonym "[211At]OKT10-B10" @default.
- NCIT_C165280 inSubset NCIT_C116977 @default.
- NCIT_C165280 inSubset NCIT_C116978 @default.
- NCIT_C165280 inSubset NCIT_C128784 @default.
- NCIT_C165280 inSubset NCIT_C157711 @default.
- NCIT_C165280 inSubset NCIT_C157712 @default.
- NCIT_C165280 inSubset NCIT_C176424 @default.
- NCIT_C165280 inSubset NCIT_C177537 @default.
- NCIT_C165280 type Class @default.
- NCIT_C165280 isDefinedBy ncit.owl @default.
- NCIT_C165280 label "Astatine At 211 Anti-CD38 Monoclonal Antibody OKT10-B10" @default.
- NCIT_C165280 subClassOf NCIT_C129819 @default.
- NCIT_C165280 subClassOf NCIT_C1446 @default.
- NCIT_C165280 subClassOf NCIT_C1511 @default.
- NCIT_C165280 subClassOf NCIT_C1512 @default.
- NCIT_C165280 subClassOf NCIT_C165280 @default.
- NCIT_C165280 subClassOf NCIT_C1908 @default.
- NCIT_C165280 subClassOf NCIT_C1909 @default.
- NCIT_C165280 subClassOf NCIT_C200225 @default.
- NCIT_C165280 subClassOf NCIT_C2124 @default.
- NCIT_C165280 subClassOf NCIT_C274 @default.
- NCIT_C165280 subClassOf NCIT_C307 @default.
- NCIT_C165280 subClassOf NCIT_C308 @default.