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- NCIT_C165647 IAO_0000115 "A radioimmunoconjugate containing the recombinant immunoglobulin G1 (IgG1) kappa humanized monoclonal antibody h11B6 that targets human kallikrein-2 (HK2) conjugated with the bifunctional, macrocyclic chelating agent tetra-azacyclododecanetetra-acetic acid (DOTA) and labeled with the radioisotope indium In 111, with potential use as an imaging agent. Upon administration of indium In 111-DOTA-h11B6, the h11B6 moiety targets and binds to HK2. Upon binding and radioimaging, HK2-expressing tumor cells can be visualized and the binding of h11B6 can be assessed. HK2 is overexpressed on a variety of cancer cells." @default.
- NCIT_C165647 NCIT_A7 NCIT_C18163 @default.
- NCIT_C165647 NCIT_NHC0 "C165647" @default.
- NCIT_C165647 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C165647 NCIT_P106 "Indicator, Reagent, or Diagnostic Aid" @default.
- NCIT_C165647 NCIT_P107 "Indium In 111-DOTA-h11B6" @default.
- NCIT_C165647 NCIT_P108 "Indium In 111-DOTA-h11B6" @default.
- NCIT_C165647 NCIT_P208 "CL978950" @default.
- NCIT_C165647 NCIT_P322 "CTRP" @default.
- NCIT_C165647 NCIT_P329 "799793" @default.
- NCIT_C165647 NCIT_P330 "799793" @default.
- NCIT_C165647 NCIT_P399 "799793" @default.
- NCIT_C165647 normalizedInformationContent "100" @default.
- NCIT_C165647 referenceCount "1" @default.
- NCIT_C165647 hasExactSynonym "111In-DOTA-h11B6" @default.
- NCIT_C165647 hasExactSynonym "Indium In 111-DOTA-h11B6" @default.
- NCIT_C165647 hasExactSynonym "Indium-111 Radiolabeled h11B6" @default.
- NCIT_C165647 inSubset NCIT_C116977 @default.
- NCIT_C165647 inSubset NCIT_C116978 @default.
- NCIT_C165647 inSubset NCIT_C176424 @default.
- NCIT_C165647 type Class @default.
- NCIT_C165647 isDefinedBy ncit.owl @default.
- NCIT_C165647 label "Indium In 111-DOTA-h11B6" @default.
- NCIT_C165647 subClassOf NCIT_C1446 @default.
- NCIT_C165647 subClassOf NCIT_C1511 @default.
- NCIT_C165647 subClassOf NCIT_C1512 @default.
- NCIT_C165647 subClassOf NCIT_C165647 @default.
- NCIT_C165647 subClassOf NCIT_C1908 @default.
- NCIT_C165647 subClassOf NCIT_C1909 @default.
- NCIT_C165647 subClassOf NCIT_C2124 @default.
- NCIT_C165647 subClassOf NCIT_C307 @default.
- NCIT_C165647 subClassOf NCIT_C308 @default.