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- NCIT_C165676 IAO_0000115 "An immediate-release (IR) tablet formulation of the aminoketone bupropion, with antidepressant activity and for potential use in promoting smoking cessation, increasing sexual desire, and reducing cancer-related fatigue. Bupropion is a weak blocker of the neuronal uptake of serotonin, dopamine and norepinephrine, and is a central nicotinic acetylcholine receptor antagonist. Bupropion may also reduce circulating levels of tumor necrosis factor (TNF) and normalize hypothalamic-pituitary-adrenal (HPA) axis functioning, which is dysregulated in certain cases of cancer-related fatigue." @default.
- NCIT_C165676 NCIT_NHC0 "C165676" @default.
- NCIT_C165676 NCIT_P106 "Organic Chemical" @default.
- NCIT_C165676 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C165676 NCIT_P107 "Immediate-release Bupropion" @default.
- NCIT_C165676 NCIT_P108 "Immediate-release Bupropion" @default.
- NCIT_C165676 NCIT_P208 "CL978941" @default.
- NCIT_C165676 NCIT_P322 "CTRP" @default.
- NCIT_C165676 NCIT_P329 "800123" @default.
- NCIT_C165676 NCIT_P330 "800123" @default.
- NCIT_C165676 NCIT_P399 "800123" @default.
- NCIT_C165676 normalizedInformationContent "100" @default.
- NCIT_C165676 referenceCount "1" @default.
- NCIT_C165676 hasExactSynonym "Bupropion Immediate Release" @default.
- NCIT_C165676 hasExactSynonym "IR Bupropion" @default.
- NCIT_C165676 hasExactSynonym "Immediate-release Bupropion" @default.
- NCIT_C165676 inSubset NCIT_C116977 @default.
- NCIT_C165676 inSubset NCIT_C116978 @default.
- NCIT_C165676 inSubset NCIT_C176424 @default.
- NCIT_C165676 type Class @default.
- NCIT_C165676 isDefinedBy ncit.owl @default.
- NCIT_C165676 label "Immediate-release Bupropion" @default.
- NCIT_C165676 subClassOf NCIT_C165676 @default.
- NCIT_C165676 subClassOf NCIT_C1908 @default.
- NCIT_C165676 subClassOf NCIT_C1909 @default.
- NCIT_C165676 subClassOf NCIT_C265 @default.
- NCIT_C165676 subClassOf NCIT_C78272 @default.