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- NCIT_C166377 IAO_0000115 "A synthetic form of the plant-derived medicinal agent, plumbagin, with potential antineoplastic activity. Plumbagin may act by inhibiting the expression of protein kinase C epsilon (PKCe), signal transducers and activators of transcription 3 phosphorylation (Stat3), protein kinase B (AKT), and certain epithelial-to-mesenchymal transition (EMT) markers, including vimentin and slug. This results in possible inhibition of proliferation in susceptible tumor cells. PKCe, Stat3, AKT, and the EMT markers vimentin and slug have been linked to the induction and progression of prostate cancer." @default.
- NCIT_C166377 NCIT_A32 NCIT_C1909 @default.
- NCIT_C166377 NCIT_A7 NCIT_C114339 @default.
- NCIT_C166377 NCIT_A7 NCIT_C28664 @default.
- NCIT_C166377 NCIT_A7 NCIT_C41625 @default.
- NCIT_C166377 NCIT_A7 NCIT_C48797 @default.
- NCIT_C166377 NCIT_A7 NCIT_C50880 @default.
- NCIT_C166377 NCIT_NHC0 "C166377" @default.
- NCIT_C166377 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C166377 NCIT_P107 "Synthetic Plumbagin PCUR-101" @default.
- NCIT_C166377 NCIT_P108 "Synthetic Plumbagin PCUR-101" @default.
- NCIT_C166377 NCIT_P208 "CL971629" @default.
- NCIT_C166377 NCIT_P210 "481-42-5" @default.
- NCIT_C166377 NCIT_P319 "YAS4TBQ4OQ" @default.
- NCIT_C166377 NCIT_P322 "CTRP" @default.
- NCIT_C166377 NCIT_P322 "FDA" @default.
- NCIT_C166377 NCIT_P322 "GDC" @default.
- NCIT_C166377 NCIT_P329 "792711" @default.
- NCIT_C166377 NCIT_P330 "792711" @default.
- NCIT_C166377 NCIT_P375 "Synthetic Plumbagin PCUR-101" @default.
- NCIT_C166377 NCIT_P399 "792711" @default.
- NCIT_C166377 normalizedInformationContent "100" @default.
- NCIT_C166377 referenceCount "1" @default.
- NCIT_C166377 hasExactSynonym "PCUR 101" @default.
- NCIT_C166377 hasExactSynonym "PCUR-101" @default.
- NCIT_C166377 hasExactSynonym "PCUR101" @default.
- NCIT_C166377 hasExactSynonym "PLUMBAGIN" @default.
- NCIT_C166377 hasExactSynonym "Synthetic Plumbagin PCUR-101" @default.
- NCIT_C166377 inSubset NCIT_C116977 @default.
- NCIT_C166377 inSubset NCIT_C116978 @default.
- NCIT_C166377 inSubset NCIT_C128784 @default.
- NCIT_C166377 inSubset NCIT_C157711 @default.
- NCIT_C166377 inSubset NCIT_C157712 @default.
- NCIT_C166377 inSubset NCIT_C176424 @default.
- NCIT_C166377 inSubset NCIT_C177537 @default.
- NCIT_C166377 inSubset NCIT_C63923 @default.
- NCIT_C166377 type Class @default.
- NCIT_C166377 isDefinedBy ncit.owl @default.
- NCIT_C166377 label "Synthetic Plumbagin PCUR-101" @default.
- NCIT_C166377 subClassOf NCIT_C166377 @default.
- NCIT_C166377 subClassOf NCIT_C1908 @default.
- NCIT_C166377 subClassOf NCIT_C1909 @default.
- NCIT_C166377 subClassOf NCIT_C2189 @default.
- NCIT_C166377 subClassOf NCIT_C274 @default.