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- NCIT_C16687 IAO_0000115 "Major protein component of chromatin. Highly conserved basic proteins, originally classified into classes based on the relative amounts of arginine and lysine in each protein. The various classes are now termed H1, H2A, H2B, H3, and H4. In chromatin, they are found in an octamer, containing two each of H2A, H2B, H3, and H4, complexed with DNA in nucleosomes. The histones in the octamer complex are also known as the core histones. The H1 class of histones, termed the linker histones, is loosely associated with the nucleosome." @default.
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- NCIT_C16687 NCIT_NHC0 "C16687" @default.
- NCIT_C16687 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C16687 NCIT_P107 "Histone" @default.
- NCIT_C16687 NCIT_P108 "Histone" @default.
- NCIT_C16687 NCIT_P207 "C0019652" @default.
- NCIT_C16687 NCIT_P322 "CDISC" @default.
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- NCIT_C16687 NCIT_P325 "A type of protein found in chromosomes. Histones bind to DNA, help give chromosomes their shape, and help control the activity of genes." @default.
- NCIT_C16687 NCIT_P325 "Any antigen(s) of the histone nuclear protein family. They can be considered as autoantigens and are commonly associated with the autoimmune diseases systemic lupus erythematosus and rheumatoid arthritis." @default.
- NCIT_C16687 NCIT_P366 "Histone" @default.
- NCIT_C16687 NCIT_P368 "CHEBI:15358" @default.
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- NCIT_C16687 referenceCount "82" @default.
- NCIT_C16687 hasExactSynonym "HISTONE" @default.
- NCIT_C16687 hasExactSynonym "Histone" @default.
- NCIT_C16687 hasExactSynonym "histone family" @default.
- NCIT_C16687 hasExactSynonym "histone" @default.
- NCIT_C16687 hasExactSynonym "histone_family" @default.
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- NCIT_C16687 type Class @default.
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- NCIT_C16687 label "Histone" @default.
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