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- NCIT_C1672 IAO_0000115 "An indium 111 radioconjugate of pentetreotide, the diethylenetriaminopentaacetic (DTPA) conjugate of the human hormone somatostatin peptide analogue (octreotide), used for radioimaging neuroendocrine tumor cells. The pentetreotide moiety of indium In 111 pentetreotide binds to somatostatin receptors (SSTRs), especially type 2 receptors, present on the cell membranes of many types of neuroendocrine tumor cells. Upon binding and internalization, this radioconjugate allows for specific imaging of neuroendocrine tumors that overexpress somatostatin using scintigraphic imaging techniques. In addition, high dose indium In 111 pentetreotide may specifically deliver a cytotoxic dose of gamma radiation to SSTR-positive cells thereby killing SSTR-expressing tumor cells." @default.
- NCIT_C1672 NCIT_A7 NCIT_C17333 @default.
- NCIT_C1672 NCIT_A7 NCIT_C17922 @default.
- NCIT_C1672 NCIT_NHC0 "C1672" @default.
- NCIT_C1672 NCIT_P106 "Indicator, Reagent, or Diagnostic Aid" @default.
- NCIT_C1672 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C1672 NCIT_P107 "Indium In-111 Pentetreotide" @default.
- NCIT_C1672 NCIT_P108 "Indium In-111 Pentetreotide" @default.
- NCIT_C1672 NCIT_P207 "C0379955" @default.
- NCIT_C1672 NCIT_P210 "139096-04-1" @default.
- NCIT_C1672 NCIT_P319 "M312JJ6Z32" @default.
- NCIT_C1672 NCIT_P322 "CTRP" @default.
- NCIT_C1672 NCIT_P322 "FDA" @default.
- NCIT_C1672 NCIT_P325 "An anticancer drug belonging to a family of drugs called radiopharmaceuticals." @default.
- NCIT_C1672 NCIT_P329 "43127" @default.
- NCIT_C1672 NCIT_P330 "43127" @default.
- NCIT_C1672 NCIT_P350 "C63H83N13O19S2."H".In" @default.
- NCIT_C1672 NCIT_P366 "In_111_Pentetreotide" @default.
- NCIT_C1672 NCIT_P399 "43127" @default.
- NCIT_C1672 normalizedInformationContent "100" @default.
- NCIT_C1672 referenceCount "1" @default.
- NCIT_C1672 hasExactSynonym "INDIUM IN-111 PENTETREOTIDE" @default.
- NCIT_C1672 hasExactSynonym "Indium In 111 Pentetreotide" @default.
- NCIT_C1672 hasExactSynonym "Indium In 111-Pentetreotide" @default.
- NCIT_C1672 hasExactSynonym "Indium In-111 Pentetreotide" @default.
- NCIT_C1672 hasExactSynonym "Indium-111-DTPA-D-Phe-1-octreotide" @default.
- NCIT_C1672 hasExactSynonym "Indium-In 111 Pentetreotide" @default.
- NCIT_C1672 hasExactSynonym "Indium-In-111-Pentetreotide" @default.
- NCIT_C1672 hasExactSynonym "OctreoScan" @default.
- NCIT_C1672 hasExactSynonym "indium In 111 pentetreotide" @default.
- NCIT_C1672 inSubset NCIT_C116977 @default.
- NCIT_C1672 inSubset NCIT_C116978 @default.
- NCIT_C1672 inSubset NCIT_C176424 @default.
- NCIT_C1672 inSubset NCIT_C63923 @default.
- NCIT_C1672 type Class @default.
- NCIT_C1672 isDefinedBy ncit.owl @default.
- NCIT_C1672 label "Indium In-111 Pentetreotide" @default.
- NCIT_C1672 subClassOf NCIT_C1446 @default.
- NCIT_C1672 subClassOf NCIT_C1672 @default.
- NCIT_C1672 subClassOf NCIT_C1908 @default.
- NCIT_C1672 subClassOf NCIT_C1909 @default.
- NCIT_C1672 subClassOf NCIT_C2124 @default.