Matches in Ubergraph for { <http://purl.obolibrary.org/obo/NCIT_C1679> ?p ?o ?g. }
Showing items 1 to 48 of
48
with 100 items per page.
- NCIT_C1679 IAO_0000115 "A semisynthetic, water-soluble derivative of camptothecin with antineoplastic activity. Exatecan mesylate inhibits topoisomerase I activity by stabilizing the cleavable complex between topoisomerase I and DNA and inhibiting religation of DNA breaks, thereby inhibiting DNA replication and triggering apoptotic cell death. This agent does not require enzymatic activation and exhibits greater potency than camptothecin and other camptothecin analogues. (NCI04)" @default.
- NCIT_C1679 NCIT_A32 NCIT_C1909 @default.
- NCIT_C1679 NCIT_A6 NCIT_C66720 @default.
- NCIT_C1679 NCIT_NHC0 "C1679" @default.
- NCIT_C1679 NCIT_P106 "Organic Chemical" @default.
- NCIT_C1679 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C1679 NCIT_P108 "Exatecan Mesylate" @default.
- NCIT_C1679 NCIT_P207 "C0935945" @default.
- NCIT_C1679 NCIT_P210 "197720-53-9" @default.
- NCIT_C1679 NCIT_P319 "D2VJ1CC26Q" @default.
- NCIT_C1679 NCIT_P322 "FDA" @default.
- NCIT_C1679 NCIT_P322 "GDC" @default.
- NCIT_C1679 NCIT_P325 "An anticancer drug that is a type of topoisomerase inhibitor." @default.
- NCIT_C1679 NCIT_P329 "43386" @default.
- NCIT_C1679 NCIT_P330 "43386" @default.
- NCIT_C1679 NCIT_P350 "C24H22FN3O4.CH4O3S.2H2O" @default.
- NCIT_C1679 NCIT_P366 "Exatecan_Mesylate" @default.
- NCIT_C1679 NCIT_P375 "Exatecan Mesylate" @default.
- NCIT_C1679 NCIT_P399 "43386" @default.
- NCIT_C1679 normalizedInformationContent "95.413332725061409" @default.
- NCIT_C1679 referenceCount "2" @default.
- NCIT_C1679 hasExactSynonym "10H,13H-Benzo(de)pyrano(3'm4':6,7)indolizino(1,2-b)quinoline-10,13-dione, 1-amino-9-ethyl-5-fluoro-1,2,3,9,12,15-hexahydro-9-hydroxy-4-methyl-, (1S-trans)-, Methanesulfonate (1:1) (Salt), Dihydrate" @default.
- NCIT_C1679 hasExactSynonym "DX-8951f" @default.
- NCIT_C1679 hasExactSynonym "EXATECAN MESYLATE" @default.
- NCIT_C1679 hasExactSynonym "Exatecan Mesylate Dihydrate" @default.
- NCIT_C1679 hasExactSynonym "Exatecan Mesylate Hydrate" @default.
- NCIT_C1679 hasExactSynonym "Exatecan Mesylate" @default.
- NCIT_C1679 hasExactSynonym "exatecan mesylate" @default.
- NCIT_C1679 inSubset NCIT_C128784 @default.
- NCIT_C1679 inSubset NCIT_C157711 @default.
- NCIT_C1679 inSubset NCIT_C157712 @default.
- NCIT_C1679 inSubset NCIT_C176424 @default.
- NCIT_C1679 inSubset NCIT_C177537 @default.
- NCIT_C1679 inSubset NCIT_C63923 @default.
- NCIT_C1679 type Class @default.
- NCIT_C1679 isDefinedBy ncit.owl @default.
- NCIT_C1679 label "Exatecan Mesylate" @default.
- NCIT_C1679 subClassOf NCIT_C129824 @default.
- NCIT_C1679 subClassOf NCIT_C129825 @default.
- NCIT_C1679 subClassOf NCIT_C1679 @default.
- NCIT_C1679 subClassOf NCIT_C1748 @default.
- NCIT_C1679 subClassOf NCIT_C1904 @default.
- NCIT_C1679 subClassOf NCIT_C1908 @default.
- NCIT_C1679 subClassOf NCIT_C1909 @default.
- NCIT_C1679 subClassOf NCIT_C2189 @default.
- NCIT_C1679 subClassOf NCIT_C274 @default.
- NCIT_C1679 subClassOf NCIT_C2843 @default.
- NCIT_C1679 subClassOf NCIT_C471 @default.