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- NCIT_C1680 IAO_0000115 "A recombinant therapeutic agent which is chemically identical to or similar to the endogenous cytokine interleukin-18 (IL-18). Produced primarily by macrophages, IL-18 induces the production of interferon-gamma (IFN-gamma), and enhances the activity of natural killer (NK) and cytotoxic T lymphocytes (CTL). As a potential immunotherapeutic agent, iboctadekin displays antitumor effects in vitro and in animal models. (NCI04)" @default.
- NCIT_C1680 NCIT_A32 NCIT_C1909 @default.
- NCIT_C1680 NCIT_NHC0 "C1680" @default.
- NCIT_C1680 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C1680 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C1680 NCIT_P107 "Iboctadekin" @default.
- NCIT_C1680 NCIT_P108 "Iboctadekin" @default.
- NCIT_C1680 NCIT_P207 "C1527127" @default.
- NCIT_C1680 NCIT_P210 "479198-61-3" @default.
- NCIT_C1680 NCIT_P319 "X08H9UZ7TO" @default.
- NCIT_C1680 NCIT_P322 "CTRP" @default.
- NCIT_C1680 NCIT_P322 "FDA" @default.
- NCIT_C1680 NCIT_P322 "GDC" @default.
- NCIT_C1680 NCIT_P329 "386168" @default.
- NCIT_C1680 NCIT_P330 "386168" @default.
- NCIT_C1680 NCIT_P366 "Therapeutic_Interleukin-18" @default.
- NCIT_C1680 NCIT_P375 "Iboctadekin" @default.
- NCIT_C1680 NCIT_P375 "Recombinant Interleukin-18" @default.
- NCIT_C1680 NCIT_P399 "386168" @default.
- NCIT_C1680 NCIT_R125 NCIT_C17828 @default.
- NCIT_C1680 NCIT_R125 NCIT_C18081 @default.
- NCIT_C1680 NCIT_R125 NCIT_C20480 @default.
- NCIT_C1680 NCIT_R125 NCIT_C20751 @default.
- NCIT_C1680 normalizedInformationContent "100" @default.
- NCIT_C1680 referenceCount "1" @default.
- NCIT_C1680 hasExactSynonym "Human Interleukin-18 (Recombinant, Expressed in Escherichia coli)" @default.
- NCIT_C1680 hasExactSynonym "Human Recombinant Interleukin-18" @default.
- NCIT_C1680 hasExactSynonym "IBOCTADEKIN" @default.
- NCIT_C1680 hasExactSynonym "IFN-Gamma-Inducing Factor" @default.
- NCIT_C1680 hasExactSynonym "IL-18" @default.
- NCIT_C1680 hasExactSynonym "Iboctadekin" @default.
- NCIT_C1680 hasExactSynonym "Interferon-Gamma-Inducing Factor" @default.
- NCIT_C1680 hasExactSynonym "Interleukin-18" @default.
- NCIT_C1680 hasExactSynonym "Recombinant Interleukin-18" @default.
- NCIT_C1680 hasExactSynonym "SB 485232" @default.
- NCIT_C1680 hasExactSynonym "SB-485232" @default.
- NCIT_C1680 inSubset NCIT_C116977 @default.
- NCIT_C1680 inSubset NCIT_C116978 @default.
- NCIT_C1680 inSubset NCIT_C128784 @default.
- NCIT_C1680 inSubset NCIT_C157711 @default.
- NCIT_C1680 inSubset NCIT_C157712 @default.
- NCIT_C1680 inSubset NCIT_C176424 @default.
- NCIT_C1680 inSubset NCIT_C177537 @default.
- NCIT_C1680 inSubset NCIT_C63923 @default.
- NCIT_C1680 type Class @default.
- NCIT_C1680 isDefinedBy ncit.owl @default.
- NCIT_C1680 label "Iboctadekin" @default.
- NCIT_C1680 subClassOf NCIT_C1283 @default.
- NCIT_C1680 subClassOf NCIT_C1680 @default.
- NCIT_C1680 subClassOf NCIT_C1908 @default.
- NCIT_C1680 subClassOf NCIT_C1909 @default.
- NCIT_C1680 subClassOf NCIT_C307 @default.
- NCIT_C1680 subClassOf NCIT_C308 @default.
- NCIT_C1680 subClassOf NCIT_C593 @default.