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- NCIT_C16995 IAO_0000115 "Tissue-type plasminogen activator (562 aa, ~63 kDa) is encoded by the human PLAT gene. This protein plays a role in the cleavage of plasminogen between Arg-580 and Val-581 to form the fibrinolytic enzyme plasmin." @default.
- NCIT_C16995 NCIT_NHC0 "C16995" @default.
- NCIT_C16995 NCIT_P100 "173370" @default.
- NCIT_C16995 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C16995 NCIT_P106 "Enzyme" @default.
- NCIT_C16995 NCIT_P107 "Tissue-Type Plasminogen Activator" @default.
- NCIT_C16995 NCIT_P108 "Tissue-Type Plasminogen Activator" @default.
- NCIT_C16995 NCIT_P208 "CL507763" @default.
- NCIT_C16995 NCIT_P322 "CTRP" @default.
- NCIT_C16995 NCIT_P325 "An enzyme made in the body that helps dissolve blood clots. A form of this enzyme is made in the laboratory to treat heart attacks, strokes, and clots in the lungs. It is also being studied in the treatment of cancer. Tissue plasminogen activator is a type of systemic thrombolytic agent." @default.
- NCIT_C16995 NCIT_P366 "Tissue_Plasminogen_Activator" @default.
- NCIT_C16995 NCIT_P93 "P00750" @default.
- NCIT_C16995 NCIT_P98 "Tissue-type plasminogen activator is synthesized as a single chain which is cleaved by plasmin, tissue kallikrein or factor Xa to a two chain disulfide linked protein. The two chain form demonstrates increased levels of plasminogen-plasmin converting activity when compared to the single chain form." @default.
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- NCIT_C16995 hasExactSynonym "EC 3.4.21.68" @default.
- NCIT_C16995 hasExactSynonym "PLAT" @default.
- NCIT_C16995 hasExactSynonym "T-Plasminogen Activator" @default.
- NCIT_C16995 hasExactSynonym "TPA" @default.
- NCIT_C16995 hasExactSynonym "Tissue Plasminogen Activator" @default.
- NCIT_C16995 hasExactSynonym "Tissue-Type Plasminogen Activator" @default.
- NCIT_C16995 hasExactSynonym "t-PA" @default.
- NCIT_C16995 hasExactSynonym "tPA" @default.
- NCIT_C16995 hasExactSynonym "tissue plasminogen activator" @default.
- NCIT_C16995 inSubset NCIT_C116977 @default.
- NCIT_C16995 inSubset NCIT_C142799 @default.
- NCIT_C16995 inSubset NCIT_C142800 @default.
- NCIT_C16995 type Class @default.
- NCIT_C16995 isDefinedBy ncit.owl @default.
- NCIT_C16995 label "Tissue-Type Plasminogen Activator" @default.
- NCIT_C16995 subClassOf NCIT_C16554 @default.
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