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- NCIT_C170048 IAO_0000115 "The sodium salt form of ibuprofen, a propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic activities. Upon administration, ibuprofen inhibits the activity of cyclo-oxygenase I and II, resulting in a decreased formation of precursors of prostaglandins and thromboxanes. This leads to decreased prostaglandin synthesis, by prostaglandin synthase, the main physiologic effect of ibuprofen. Ibuprofen also causes a decrease in the formation of thromboxane A2 synthesis, by thromboxane synthase, thereby inhibiting platelet aggregation." @default.
- NCIT_C170048 NCIT_NHC0 "C170048" @default.
- NCIT_C170048 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C170048 NCIT_P108 "Ibuprofen Sodium" @default.
- NCIT_C170048 NCIT_P208 "CL1382278" @default.
- NCIT_C170048 NCIT_P210 "527688-20-6" @default.
- NCIT_C170048 NCIT_P319 "RM1CE97Z4N" @default.
- NCIT_C170048 NCIT_P322 "FDA" @default.
- NCIT_C170048 normalizedInformationContent "100" @default.
- NCIT_C170048 referenceCount "1" @default.
- NCIT_C170048 hasExactSynonym "IBUPROFEN SODIUM" @default.
- NCIT_C170048 hasExactSynonym "Ibuprofen Sodium" @default.
- NCIT_C170048 inSubset NCIT_C173381 @default.
- NCIT_C170048 inSubset NCIT_C173383 @default.
- NCIT_C170048 inSubset NCIT_C63923 @default.
- NCIT_C170048 type Class @default.
- NCIT_C170048 isDefinedBy ncit.owl @default.
- NCIT_C170048 label "Ibuprofen Sodium" @default.
- NCIT_C170048 subClassOf NCIT_C1323 @default.
- NCIT_C170048 subClassOf NCIT_C170048 @default.
- NCIT_C170048 subClassOf NCIT_C1908 @default.
- NCIT_C170048 subClassOf NCIT_C1909 @default.
- NCIT_C170048 subClassOf NCIT_C2198 @default.
- NCIT_C170048 subClassOf NCIT_C2356 @default.
- NCIT_C170048 subClassOf NCIT_C241 @default.
- NCIT_C170048 subClassOf NCIT_C257 @default.
- NCIT_C170048 subClassOf NCIT_C471 @default.
- NCIT_C170048 subClassOf NCIT_C78272 @default.