Matches in Ubergraph for { <http://purl.obolibrary.org/obo/NCIT_C17063> ?p ?o ?g. }
- NCIT_C17063 IAO_0000115 "Androgen receptor (919 aa, ~99 kDa) is encoded by the human AR gene. This protein plays a role in the modulation of steroid-dependent gene transcription." @default.
- NCIT_C17063 NCIT_NHC0 "C17063" @default.
- NCIT_C17063 NCIT_P100 "313700" @default.
- NCIT_C17063 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C17063 NCIT_P106 "Receptor" @default.
- NCIT_C17063 NCIT_P107 "Androgen Receptor" @default.
- NCIT_C17063 NCIT_P108 "Androgen Receptor" @default.
- NCIT_C17063 NCIT_P207 "C0034786" @default.
- NCIT_C17063 NCIT_P322 "CTRP" @default.
- NCIT_C17063 NCIT_P366 "Androgen_Receptor" @default.
- NCIT_C17063 NCIT_P93 "P10275" @default.
- NCIT_C17063 NCIT_P98 "AR has 3 domains: N-terminal modulating (exon 1), DNA-binding (two C4 Zinc fingers, exons 2-3), and C-terminal hormone-binding (5 remaining exons). Polymorphic N-terminal poly-Gln tracts bind RAN, enhancing transactivation; decreased with increased poly-Gln length. An 87-kD (AR-A) isoform lacks a normal N-terminus, seen in the 110 kD (AR-B) form; A and B may differ in function. Ligand bound receptor translocates to the nucleus, homodimerizes, binds DNA, and stimulates transcription." @default.
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