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- NCIT_C17064 IAO_0000115 "Proto-oncogene Mas (325 aa, ~37 kDa) is encoded by the human MAS1 gene. This protein is involved in angiotensin binding and G protein-coupled receptor signaling." @default.
- NCIT_C17064 NCIT_NHC0 "C17064" @default.
- NCIT_C17064 NCIT_P100 "165180" @default.
- NCIT_C17064 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C17064 NCIT_P106 "Receptor" @default.
- NCIT_C17064 NCIT_P108 "Proto-Oncogene Mas" @default.
- NCIT_C17064 NCIT_P207 "C1622222" @default.
- NCIT_C17064 NCIT_P366 "MAS1_Protein" @default.
- NCIT_C17064 NCIT_P93 "P04201" @default.
- NCIT_C17064 NCIT_P98 "A product of the MAS1 Gene, an oncogene isolated from DNA of a human epidermoid carcinoma cell line. Based on its deduced amino acid sequence, the MAS1 gene product contains 7 potential transmembrane domains. The MAS1 protein is, therefore, probably an integral membrane protein. The structure of the MAS oncogene indicates that it belongs to the class of receptors that are coupled to GTP-binding proteins and share a conserved structural motif, which is described as a '7-transmembrane segment' following the prediction that these hydrophobic segments form membrane-spanning alpha-helices. It is predicted that it would encode a peptide receptor with mitogenic activity which would act through the inositol lipid signaling pathways. Expression in Xenopus oocytes and a transfected mammalian cell line demonstrated that the MAS gene product is a functional angiotensin receptor. (from OMIM)" @default.
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- NCIT_C17064 hasExactSynonym "Angiotensin Receptor" @default.
- NCIT_C17064 hasExactSynonym "MAS Proto-Oncogene" @default.
- NCIT_C17064 hasExactSynonym "MAS1 Gene Product" @default.
- NCIT_C17064 hasExactSynonym "MAS1 Protein" @default.
- NCIT_C17064 hasExactSynonym "MAS1" @default.
- NCIT_C17064 hasExactSynonym "Mas-Related G Protein-Coupled Receptor A" @default.
- NCIT_C17064 hasExactSynonym "Proto-Oncogene Mas" @default.
- NCIT_C17064 type Class @default.
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- NCIT_C17064 label "Proto-Oncogene Mas" @default.
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