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Matches in Ubergraph for { <http://purl.obolibrary.org/obo/NCIT_C17068> ?p ?o ?g. }

• NCIT_C17068 IAO_0000115 "Epidermal growth factor receptor (1210 aa, ~134 kDa) is encoded by the human EGFR gene. This protein plays a role in cell-cell adhesion, cell migration, cell proliferation and signal transduction." @default.
• NCIT_C17068 NCIT_NHC0 "C17068" @default.
• NCIT_C17068 NCIT_P100 "131550" @default.
• NCIT_C17068 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
• NCIT_C17068 NCIT_P106 "Enzyme" @default.
• NCIT_C17068 NCIT_P106 "Receptor" @default.
• NCIT_C17068 NCIT_P107 "Epidermal Growth Factor Receptor" @default.
• NCIT_C17068 NCIT_P108 "Epidermal Growth Factor Receptor" @default.
• NCIT_C17068 NCIT_P207 "C1739039" @default.
• NCIT_C17068 NCIT_P322 "CTRP" @default.
• NCIT_C17068 NCIT_P325 "The protein found on the surface of some cells and to which epidermal growth factor binds, causing the cells to divide. It is found at abnormally high levels on the surface of many types of cancer cells, so these cells may divide excessively in the presence of epidermal growth factor." @default.
• NCIT_C17068 NCIT_P366 "Epidermal_Growth_Factor_Receptor" @default.
• NCIT_C17068 NCIT_P93 "P00533" @default.
• NCIT_C17068 NCIT_P98 "The Epidermal Growth Factor Receptor is a protein tyrosine kinase with two glycoprotein components of different molecular weight; both contain phosphotyrosine and phosphothreonine but only the higher molecular weight form contains phosphoserine. The tyrosine kinase activity is required for internalization or degradation of EGF-EGFR receptor complexes. EGF stimulation of the receptor initiates DNA and protein synthesis in target cells. The receptor is not found on mitotically quiescent cells except the stomach where it controls synthesis and release of digestive enzymes and gastric acid. TGF alpha also binds to and activates the receptor." @default.
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