Matches in Ubergraph for { <http://purl.obolibrary.org/obo/NCIT_C17069> ?p ?o ?g. }
- NCIT_C17069 IAO_0000115 "Widely expressed human Estrogen Receptors (NR3 Family) are cytoplasmic hormone-activated receptors that act as nuclear transcription factors composed of an N-terminal transcription activation/modulation domain, a DNA-binding domain, and a C-terminal steroid-binding domain. Binding to DNA as a homo- or heterodimer, ESR interacts with NCOA3, NCOA5, and NCOA6 coactivators. Hormone-ESR complexes appear to recognize discrete upstream target ERE DNA sequences to regulate gene expression, cell proliferation, and differentiation. DNA-binding is lost in the absence of ligand. (NCI)" @default.
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- NCIT_C17069 hasExactSynonym "ER Family" @default.
- NCIT_C17069 hasExactSynonym "ER" @default.
- NCIT_C17069 hasExactSynonym "Estradiol Receptor" @default.
- NCIT_C17069 hasExactSynonym "Estrogen Receptor Family Protein" @default.
- NCIT_C17069 hasExactSynonym "Estrogen Receptor Family" @default.
- NCIT_C17069 hasExactSynonym "Estrogen Receptor" @default.
- NCIT_C17069 hasExactSynonym "NR3A" @default.
- NCIT_C17069 hasExactSynonym "Nuclear Receptor Subfamily 3 Group A" @default.
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