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- NCIT_C170913 IAO_0000115 "A preparation of autologous activated T cells that have been engineered to express chimeric antigen receptors (CARs) specific for the tumor-associated antigen (TAA) CD147 (Basigin; EMMPRIN; extracellular matrix metalloproteinase inducer; OX47; 5A11), with potential antineoplastic activity. Upon administration back into the patient, the anti-CD147 CAR T-cells target and induce selective cytotoxicity in CD147-expressing tumor cells. CD147, a cell-surface glycoprotein of the immunoglobulin G (IgG) superfamily, is overexpressed in certain human tumors and plays an important role in tumor cell proliferation, migration, progression, and metastasis." @default.
- NCIT_C170913 NCIT_NHC0 "C170913" @default.
- NCIT_C170913 NCIT_P106 "Cell" @default.
- NCIT_C170913 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C170913 NCIT_P108 "Autologous Anti-CD147 CAR T-cells" @default.
- NCIT_C170913 NCIT_P208 "CL1383069" @default.
- NCIT_C170913 NCIT_P329 "800845" @default.
- NCIT_C170913 NCIT_P330 "800845" @default.
- NCIT_C170913 NCIT_P399 "800845" @default.
- NCIT_C170913 NCIT_P399 "813319" @default.
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- NCIT_C170913 normalizedInformationContent "100" @default.
- NCIT_C170913 referenceCount "1" @default.
- NCIT_C170913 hasExactSynonym "Autologous Anti-CD147 CAR T-cells" @default.
- NCIT_C170913 hasExactSynonym "Autologous CD147-CAR-expressing T-cells" @default.
- NCIT_C170913 hasExactSynonym "Autologous CD147-CART Cells" @default.
- NCIT_C170913 inSubset NCIT_C128784 @default.
- NCIT_C170913 inSubset NCIT_C176424 @default.
- NCIT_C170913 type Class @default.
- NCIT_C170913 isDefinedBy ncit.owl @default.
- NCIT_C170913 label "Autologous Anti-CD147 CAR T-cells" @default.
- NCIT_C170913 subClassOf NCIT_C129820 @default.
- NCIT_C170913 subClassOf NCIT_C129821 @default.
- NCIT_C170913 subClassOf NCIT_C129826 @default.
- NCIT_C170913 subClassOf NCIT_C137999 @default.
- NCIT_C170913 subClassOf NCIT_C142078 @default.
- NCIT_C170913 subClassOf NCIT_C154231 @default.
- NCIT_C170913 subClassOf NCIT_C170913 @default.
- NCIT_C170913 subClassOf NCIT_C1908 @default.
- NCIT_C170913 subClassOf NCIT_C1909 @default.
- NCIT_C170913 subClassOf NCIT_C1962 @default.
- NCIT_C170913 subClassOf NCIT_C200766 @default.
- NCIT_C170913 subClassOf NCIT_C274 @default.
- NCIT_C170913 subClassOf NCIT_C28681 @default.
- NCIT_C170913 subClassOf NCIT_C307 @default.
- NCIT_C170913 subClassOf NCIT_C308 @default.