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- NCIT_C170932 IAO_0000115 "A dendritic cell (DC)-based cancer vaccine against the tumor-associated antigens (TAAs) human epidermal growth factor receptor 2 (HER2; EGFR2, ERBB2) and 3 (HER3; ErbB3), with potential immunomodulatory and antineoplastic activities. Upon administration of the anti-HER2/HER3 DC vaccine, the immune system gets exposed to HER2 and HER3, which may stimulate a potent cytotoxic T-lymphocyte (CTL) response against HER-2/3-positive tumor cells. This may result in tumor cell death and decreased tumor growth. HER-2/3, members of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases, are overexpressed by a variety of cancers." @default.
- NCIT_C170932 NCIT_A7 NCIT_C17319 @default.
- NCIT_C170932 NCIT_NHC0 "C170932" @default.
- NCIT_C170932 NCIT_P106 "Cell" @default.
- NCIT_C170932 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C170932 NCIT_P107 "Anti-HER2/HER3 Dendritic Cell Vaccine" @default.
- NCIT_C170932 NCIT_P108 "Anti-HER2/HER3 Dendritic Cell Vaccine" @default.
- NCIT_C170932 NCIT_P208 "CL1383088" @default.
- NCIT_C170932 NCIT_P322 "CTRP" @default.
- NCIT_C170932 NCIT_P329 "801200" @default.
- NCIT_C170932 NCIT_P330 "801200" @default.
- NCIT_C170932 NCIT_P399 "801200" @default.
- NCIT_C170932 normalizedInformationContent "100" @default.
- NCIT_C170932 referenceCount "1" @default.
- NCIT_C170932 hasExactSynonym "Anti-HER2/3 DC Vaccine" @default.
- NCIT_C170932 hasExactSynonym "Anti-HER2/3 Dendritic Cell Vaccine" @default.
- NCIT_C170932 hasExactSynonym "Anti-HER2/HER3 Dendritic Cell Vaccine" @default.
- NCIT_C170932 inSubset NCIT_C116977 @default.
- NCIT_C170932 inSubset NCIT_C116978 @default.
- NCIT_C170932 inSubset NCIT_C128784 @default.
- NCIT_C170932 inSubset NCIT_C176424 @default.
- NCIT_C170932 type Class @default.
- NCIT_C170932 isDefinedBy ncit.owl @default.
- NCIT_C170932 label "Anti-HER2/HER3 Dendritic Cell Vaccine" @default.
- NCIT_C170932 subClassOf NCIT_C129820 @default.
- NCIT_C170932 subClassOf NCIT_C1663 @default.
- NCIT_C170932 subClassOf NCIT_C170932 @default.
- NCIT_C170932 subClassOf NCIT_C1908 @default.
- NCIT_C170932 subClassOf NCIT_C1909 @default.
- NCIT_C170932 subClassOf NCIT_C274 @default.
- NCIT_C170932 subClassOf NCIT_C28308 @default.
- NCIT_C170932 subClassOf NCIT_C28310 @default.
- NCIT_C170932 subClassOf NCIT_C307 @default.
- NCIT_C170932 subClassOf NCIT_C308 @default.
- NCIT_C170932 subClassOf NCIT_C923 @default.