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- NCIT_C171034 IAO_0000115 "A preparation of T-lymphocytes that have been genetically modified to express a chimeric antigen receptor (CAR) targeting the tumor-associated antigen (TAA) CD37 (cluster of differentiation 37), with potential immunostimulating and antineoplastic activities. Upon administration, anti-CD37-CAR T-cells specifically recognize and kill CD37-expressing tumor cells. CD37, a member of the tetraspanin superfamily of cell surface antigens, is expressed in B-cell non-Hodgkin lymphomas (NHL), in chronic lymphocytic leukemia (CLL), and in some cases of cutaneous and peripheral T-cell lymphomas. It plays a key role in tumor cell proliferation." @default.
- NCIT_C171034 NCIT_A7 NCIT_C102769 @default.
- NCIT_C171034 NCIT_NHC0 "C171034" @default.
- NCIT_C171034 NCIT_P106 "Cell" @default.
- NCIT_C171034 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C171034 NCIT_P107 "Anti-CD37-CAR-expressing T-lymphocytes" @default.
- NCIT_C171034 NCIT_P108 "Anti-CD37-CAR-expressing T-lymphocytes" @default.
- NCIT_C171034 NCIT_P208 "CL1383288" @default.
- NCIT_C171034 NCIT_P322 "CTRP" @default.
- NCIT_C171034 NCIT_P329 "801227" @default.
- NCIT_C171034 NCIT_P330 "801227" @default.
- NCIT_C171034 NCIT_P399 "801227" @default.
- NCIT_C171034 normalizedInformationContent "100" @default.
- NCIT_C171034 referenceCount "1" @default.
- NCIT_C171034 hasExactSynonym "Anti-CD37-CAR T-cells" @default.
- NCIT_C171034 hasExactSynonym "Anti-CD37-CAR-T Cells" @default.
- NCIT_C171034 hasExactSynonym "Anti-CD37-CAR-expressing T-lymphocytes" @default.
- NCIT_C171034 hasExactSynonym "CAR-37 T Cells" @default.
- NCIT_C171034 inSubset NCIT_C116977 @default.
- NCIT_C171034 inSubset NCIT_C116978 @default.
- NCIT_C171034 inSubset NCIT_C128784 @default.
- NCIT_C171034 inSubset NCIT_C176424 @default.
- NCIT_C171034 type Class @default.
- NCIT_C171034 isDefinedBy ncit.owl @default.
- NCIT_C171034 label "Anti-CD37-CAR-expressing T-lymphocytes" @default.
- NCIT_C171034 subClassOf NCIT_C129820 @default.
- NCIT_C171034 subClassOf NCIT_C129821 @default.
- NCIT_C171034 subClassOf NCIT_C129826 @default.
- NCIT_C171034 subClassOf NCIT_C137999 @default.
- NCIT_C171034 subClassOf NCIT_C142078 @default.
- NCIT_C171034 subClassOf NCIT_C154231 @default.
- NCIT_C171034 subClassOf NCIT_C171034 @default.
- NCIT_C171034 subClassOf NCIT_C1908 @default.
- NCIT_C171034 subClassOf NCIT_C1909 @default.
- NCIT_C171034 subClassOf NCIT_C1962 @default.
- NCIT_C171034 subClassOf NCIT_C274 @default.
- NCIT_C171034 subClassOf NCIT_C307 @default.
- NCIT_C171034 subClassOf NCIT_C308 @default.