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- NCIT_C1716 IAO_0000115 "A humanized recombinant monoclonal antibody directed against CD33, a cell surface antigen found on myeloid leukemia blasts and early hematopoietic progenitor cells. Lintuzumab stimulates antibody-dependent cell-mediated cytotoxicity (ADCC) against tumor cells expressing CD33, resulting in a decrease in tumor burden. The humanized version of this monoclonal antibody exhibits less immunogenicity and improved binding affinity compared to its murine counterpart." @default.
- NCIT_C1716 NCIT_A32 NCIT_C1909 @default.
- NCIT_C1716 NCIT_A7 NCIT_C97246 @default.
- NCIT_C1716 NCIT_NHC0 "C1716" @default.
- NCIT_C1716 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C1716 NCIT_P106 "Immunologic Factor" @default.
- NCIT_C1716 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C1716 NCIT_P107 "Lintuzumab" @default.
- NCIT_C1716 NCIT_P108 "Lintuzumab" @default.
- NCIT_C1716 NCIT_P207 "C0530093" @default.
- NCIT_C1716 NCIT_P210 "166089-32-3" @default.
- NCIT_C1716 NCIT_P319 "V00Y10W60W" @default.
- NCIT_C1716 NCIT_P322 "CTRP" @default.
- NCIT_C1716 NCIT_P322 "FDA" @default.
- NCIT_C1716 NCIT_P322 "GDC" @default.
- NCIT_C1716 NCIT_P325 "A substance being studied in the treatment of myelodysplastic syndromes and some types of leukemia. It binds to CD33, a protein on the surface of certain normal blood stem cells and some abnormal blood cells. It causes the immune system to kill these cells. Lintuzumab is a type of monoclonal antibody." @default.
- NCIT_C1716 NCIT_P329 "42049" @default.
- NCIT_C1716 NCIT_P330 "42049" @default.
- NCIT_C1716 NCIT_P366 "Monoclonal_Antibody_HuG1-M195" @default.
- NCIT_C1716 NCIT_P375 "Lintuzumab" @default.
- NCIT_C1716 NCIT_P399 "42049" @default.
- NCIT_C1716 NCIT_R124 NCIT_C17710 @default.
- NCIT_C1716 NCIT_R124 NCIT_C17828 @default.
- NCIT_C1716 NCIT_R124 NCIT_C18219 @default.
- NCIT_C1716 NCIT_R124 NCIT_C19986 @default.
- NCIT_C1716 NCIT_R124 NCIT_C40474 @default.
- NCIT_C1716 normalizedInformationContent "92.730304365937428" @default.
- NCIT_C1716 referenceCount "3" @default.
- NCIT_C1716 hasExactSynonym "Hu-M195 monoclonal antibody" @default.
- NCIT_C1716 hasExactSynonym "HuG1-M195 monoclonal antibody" @default.
- NCIT_C1716 hasExactSynonym "Humanized M195" @default.
- NCIT_C1716 hasExactSynonym "LINTUZUMAB" @default.
- NCIT_C1716 hasExactSynonym "Lintuzumab" @default.
- NCIT_C1716 hasExactSynonym "MoAb HuG1-M195" @default.
- NCIT_C1716 hasExactSynonym "MoAb HuM195" @default.
- NCIT_C1716 hasExactSynonym "Monoclonal Antibody HuG1-M195" @default.
- NCIT_C1716 hasExactSynonym "Monoclonal Antibody HuM195" @default.
- NCIT_C1716 hasExactSynonym "SGN-33" @default.
- NCIT_C1716 hasExactSynonym "SMART M195" @default.
- NCIT_C1716 hasExactSynonym "Zamyl" @default.
- NCIT_C1716 hasExactSynonym "lintuzumab" @default.
- NCIT_C1716 hasExactSynonym "monoclonal antibody HuM195 HuG1-M195" @default.
- NCIT_C1716 inSubset NCIT_C116977 @default.
- NCIT_C1716 inSubset NCIT_C116978 @default.
- NCIT_C1716 inSubset NCIT_C128784 @default.
- NCIT_C1716 inSubset NCIT_C157711 @default.
- NCIT_C1716 inSubset NCIT_C157712 @default.
- NCIT_C1716 inSubset NCIT_C176424 @default.
- NCIT_C1716 inSubset NCIT_C177537 @default.
- NCIT_C1716 inSubset NCIT_C63923 @default.
- NCIT_C1716 type Class @default.
- NCIT_C1716 isDefinedBy ncit.owl @default.
- NCIT_C1716 label "Lintuzumab" @default.
- NCIT_C1716 subClassOf NCIT_C129821 @default.
- NCIT_C1716 subClassOf NCIT_C129822 @default.
- NCIT_C1716 subClassOf NCIT_C1716 @default.
- NCIT_C1716 subClassOf NCIT_C1908 @default.
- NCIT_C1716 subClassOf NCIT_C1909 @default.
- NCIT_C1716 subClassOf NCIT_C200367 @default.
- NCIT_C1716 subClassOf NCIT_C20401 @default.
- NCIT_C1716 subClassOf NCIT_C274 @default.
- NCIT_C1716 subClassOf NCIT_C307 @default.
- NCIT_C1716 subClassOf NCIT_C308 @default.