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- NCIT_C171898 IAO_0000115 "The hydrochloride salt form of elacestrant, an orally available, selective estrogen receptor degrader (SERD), with antineoplastic activity. Upon oral administration, elacestrant acts as a SERD, which binds to the estrogen receptor (ER) and induces a conformational change that results in the proteosomal degradation of the receptor. This prevents ER-mediated signaling and inhibits proliferation of ER-expressing cancer cells." @default.
- NCIT_C171898 NCIT_NHC0 "C171898" @default.
- NCIT_C171898 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C171898 NCIT_P108 "Elacestrant Hydrochloride" @default.
- NCIT_C171898 NCIT_P208 "CL1406073" @default.
- NCIT_C171898 NCIT_P210 "1349723-93-8" @default.
- NCIT_C171898 NCIT_P302 "postmenopausal women or adult men with ER-positive, HER2-negative, ESR1-mutated advanced or metastatic breast cancer" @default.
- NCIT_C171898 NCIT_P319 "8NZT0PR8AL" @default.
- NCIT_C171898 NCIT_P322 "FDA" @default.
- NCIT_C171898 NCIT_P399 "768338" @default.
- NCIT_C171898 normalizedInformationContent "95.413332725061409" @default.
- NCIT_C171898 referenceCount "2" @default.
- NCIT_C171898 hasExactSynonym "ELACESTRANT HYDROCHLORIDE" @default.
- NCIT_C171898 hasExactSynonym "Elacestrant Hydrochloride" @default.
- NCIT_C171898 hasExactSynonym "Orserdu" @default.
- NCIT_C171898 hasExactSynonym "RAD-1901 Dihydrochloride" @default.
- NCIT_C171898 hasExactSynonym "RAD1901 Dihydrochloride" @default.
- NCIT_C171898 inSubset NCIT_C128784 @default.
- NCIT_C171898 inSubset NCIT_C176424 @default.
- NCIT_C171898 inSubset NCIT_C63923 @default.
- NCIT_C171898 type Class @default.
- NCIT_C171898 isDefinedBy ncit.owl @default.
- NCIT_C171898 label "Elacestrant Hydrochloride" @default.
- NCIT_C171898 subClassOf NCIT_C129818 @default.
- NCIT_C171898 subClassOf NCIT_C147908 @default.
- NCIT_C171898 subClassOf NCIT_C163758 @default.
- NCIT_C171898 subClassOf NCIT_C171898 @default.
- NCIT_C171898 subClassOf NCIT_C1821 @default.
- NCIT_C171898 subClassOf NCIT_C1892 @default.
- NCIT_C171898 subClassOf NCIT_C1908 @default.
- NCIT_C171898 subClassOf NCIT_C1909 @default.
- NCIT_C171898 subClassOf NCIT_C274 @default.
- NCIT_C171898 subClassOf NCIT_C481 @default.
- NCIT_C171898 subClassOf NCIT_C483 @default.
- NCIT_C171898 subClassOf NCIT_C547 @default.
- NCIT_C171898 subClassOf NCIT_C548 @default.