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- NCIT_C172057 IAO_0000115 "A preparation of autologous T-lymphocytes engineered to express a chimeric antigen receptor (CAR) that is nanobody-based and specific for the two tumor-associated antigens (TAAs) cluster of differentiation 19 (CD19) and CD20, with potential immunostimulating and antineoplastic activities. Upon administration, the autologous anti-CD19/CD20 bispecific nanobody-based CAR-T cells target and bind to CD19- and CD20-expressing tumor B-cells. This induces selective toxicity in tumor B-cells expressing these TAAs. Both CD19 and CD20 are B-cell-specific cell surface antigens overexpressed in B-cell lineage malignancies. Targeting both CD19 and CD20 may prevent tumor cell antigen escape and relapse." @default.
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- NCIT_C172057 NCIT_P108 "Autologous Anti-CD19/CD20 Bispecific Nanobody-based CAR-T cells" @default.
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- NCIT_C172057 NCIT_P375 "Autologous Anti-CD19/CD20 Bispecific Nanobody-based CAR-T cells" @default.
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- NCIT_C172057 hasExactSynonym "Autologous Anti-CD19/20 Bispecific CAR-T Cells" @default.
- NCIT_C172057 hasExactSynonym "Autologous Anti-CD19/CD20 Bispecific Nanobody-based CAR-T cells" @default.
- NCIT_C172057 hasExactSynonym "Autologous Anti-CD19/CD20 Bispecific Nanobody-derived CAR-T Cells" @default.
- NCIT_C172057 hasExactSynonym "Autologous CD19/CD20 Bispecific CAR-T Cells" @default.
- NCIT_C172057 inSubset NCIT_C128784 @default.
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- NCIT_C172057 type Class @default.
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- NCIT_C172057 label "Autologous Anti-CD19/CD20 Bispecific Nanobody-based CAR-T cells" @default.
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