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- NCIT_C1723 IAO_0000115 "A recombinant, chimeric monoclonal antibody directed against the epidermal growth factor (EGFR) with antineoplastic activity. Cetuximab binds to the extracellular domain of the EGFR, thereby preventing the activation and subsequent dimerization of the receptor; the decrease in receptor activation and dimerization may result in an inhibition in signal transduction and anti-proliferative effects. This agent may inhibit EGFR-dependent primary tumor growth and metastasis. EGFR is overexpressed on the cell surfaces of various solid tumors." @default.
- NCIT_C1723 NCIT_A32 NCIT_C1909 @default.
- NCIT_C1723 NCIT_A7 NCIT_C17068 @default.
- NCIT_C1723 NCIT_NHC0 "C1723" @default.
- NCIT_C1723 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C1723 NCIT_P106 "Immunologic Factor" @default.
- NCIT_C1723 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C1723 NCIT_P107 "Cetuximab" @default.
- NCIT_C1723 NCIT_P108 "Cetuximab" @default.
- NCIT_C1723 NCIT_P175 "714692" @default.
- NCIT_C1723 NCIT_P207 "C0995188" @default.
- NCIT_C1723 NCIT_P210 "205923-56-4" @default.
- NCIT_C1723 NCIT_P302 "Advanced colorectal cancer; Head and neck cancer" @default.
- NCIT_C1723 NCIT_P319 "PQX0D8J21J" @default.
- NCIT_C1723 NCIT_P322 "CTRP" @default.
- NCIT_C1723 NCIT_P322 "FDA" @default.
- NCIT_C1723 NCIT_P322 "GDC" @default.
- NCIT_C1723 NCIT_P325 "A monoclonal antibody used to treat certain types of head and neck cancer, and colorectal cancer that has spread to other parts of the body. It is also being studied in the treatment of other types of cancer. Monoclonal antibodies are made in the laboratory and can locate and bind to cancer cells. Erbitux binds to the epidermal growth factor receptor (EGFR), which is found on the surface of some types of cancer cells." @default.
- NCIT_C1723 NCIT_P329 "42384" @default.
- NCIT_C1723 NCIT_P330 "42384" @default.
- NCIT_C1723 NCIT_P366 "Cetuximab" @default.
- NCIT_C1723 NCIT_P375 "Cetuximab" @default.
- NCIT_C1723 NCIT_P399 "42384" @default.
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- NCIT_C1723 NCIT_R125 NCIT_C18839 @default.
- NCIT_C1723 NCIT_R125 NCIT_C21124 @default.
- NCIT_C1723 NCIT_R146 NCIT_C105526 @default.
- NCIT_C1723 NCIT_R146 NCIT_C16554 @default.
- NCIT_C1723 NCIT_R146 NCIT_C16984 @default.
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- NCIT_C1723 NCIT_R146 NCIT_C17660 @default.
- NCIT_C1723 NCIT_R146 NCIT_C17728 @default.
- NCIT_C1723 NCIT_R146 NCIT_C18106 @default.
- NCIT_C1723 NCIT_R146 NCIT_C18506 @default.
- NCIT_C1723 NCIT_R146 NCIT_C20027 @default.
- NCIT_C1723 NCIT_R146 NCIT_C26548 @default.
- NCIT_C1723 normalizedInformationContent "76.105970727550996" @default.
- NCIT_C1723 referenceCount "37" @default.
- NCIT_C1723 hasExactSynonym "C225" @default.
- NCIT_C1723 hasExactSynonym "CETUXIMAB" @default.
- NCIT_C1723 hasExactSynonym "Cetuximab Biosimilar CDP-1" @default.
- NCIT_C1723 hasExactSynonym "Cetuximab Biosimilar CMAB009" @default.
- NCIT_C1723 hasExactSynonym "Cetuximab Biosimilar KL 140" @default.
- NCIT_C1723 hasExactSynonym "Cetuximab" @default.
- NCIT_C1723 hasExactSynonym "Chimeric Anti-EGFR Monoclonal Antibody" @default.
- NCIT_C1723 hasExactSynonym "Chimeric MoAb C225" @default.
- NCIT_C1723 hasExactSynonym "Chimeric Monoclonal Antibody C225" @default.
- NCIT_C1723 hasExactSynonym "Erbitux" @default.
- NCIT_C1723 hasExactSynonym "IMC-C225" @default.
- NCIT_C1723 hasExactSynonym "cetuximab" @default.
- NCIT_C1723 inSubset NCIT_C116977 @default.
- NCIT_C1723 inSubset NCIT_C116978 @default.
- NCIT_C1723 inSubset NCIT_C128784 @default.
- NCIT_C1723 inSubset NCIT_C157711 @default.
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- NCIT_C1723 inSubset NCIT_C176424 @default.
- NCIT_C1723 inSubset NCIT_C177537 @default.
- NCIT_C1723 inSubset NCIT_C63923 @default.
- NCIT_C1723 type Class @default.
- NCIT_C1723 isDefinedBy ncit.owl @default.
- NCIT_C1723 label "Cetuximab" @default.
- NCIT_C1723 subClassOf B08e3a805f742e47432de5e1ebd7933b0 @default.
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