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- NCIT_C172613 IAO_0000115 "An adenosine analog and RNA polymerase inhibitor, with potential broad-spectrum antiviral activity. Upon administration, galidesivir is metabolized to its monophosphate form, which is then converted into the active triphosphate nucleotide. Galidesivir triphosphate binds to viral RNA-dependent RNA polymerase (RdRp) and gets incorporated into the growing viral RNA strand, which leads to premature chain termination. This prevents viral transcription and replication." @default.
- NCIT_C172613 NCIT_NHC0 "C172613" @default.
- NCIT_C172613 NCIT_P106 "Organic Chemical" @default.
- NCIT_C172613 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C172613 NCIT_P108 "Galidesivir" @default.
- NCIT_C172613 NCIT_P207 "C3852939" @default.
- NCIT_C172613 NCIT_P210 "249503-25-1" @default.
- NCIT_C172613 NCIT_P319 "OLF97F86A7" @default.
- NCIT_C172613 NCIT_P322 "FDA" @default.
- NCIT_C172613 normalizedInformationContent "100" @default.
- NCIT_C172613 referenceCount "1" @default.
- NCIT_C172613 hasExactSynonym "BCX 4430" @default.
- NCIT_C172613 hasExactSynonym "BCX-4430" @default.
- NCIT_C172613 hasExactSynonym "BCX4430" @default.
- NCIT_C172613 hasExactSynonym "GALIDESIVIR" @default.
- NCIT_C172613 hasExactSynonym "Galidesivir" @default.
- NCIT_C172613 hasExactSynonym "Immucillin-A" @default.
- NCIT_C172613 inSubset NCIT_C173381 @default.
- NCIT_C172613 inSubset NCIT_C173383 @default.
- NCIT_C172613 inSubset NCIT_C63923 @default.
- NCIT_C172613 type Class @default.
- NCIT_C172613 isDefinedBy ncit.owl @default.
- NCIT_C172613 label "Galidesivir" @default.
- NCIT_C172613 subClassOf NCIT_C172613 @default.
- NCIT_C172613 subClassOf NCIT_C1908 @default.
- NCIT_C172613 subClassOf NCIT_C1909 @default.
- NCIT_C172613 subClassOf NCIT_C254 @default.
- NCIT_C172613 subClassOf NCIT_C281 @default.
- NCIT_C172613 subClassOf NCIT_C29575 @default.
- NCIT_C172613 subClassOf NCIT_C471 @default.