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- NCIT_C172614 IAO_0000115 "The hydrochloride salt form of galidesivir, an adenosine analog and RNA polymerase inhibitor, with potential broad-spectrum antiviral activity. Upon administration, galidesivir is metabolized to its monophosphate form, which is then converted into the active triphosphate nucleotide. Galidesivir triphosphate binds to viral RNA-dependent RNA polymerase (RdRp) and gets incorporated into the growing viral RNA strand, which leads to premature chain termination. This prevents viral transcription and replication." @default.
- NCIT_C172614 NCIT_NHC0 "C172614" @default.
- NCIT_C172614 NCIT_P106 "Organic Chemical" @default.
- NCIT_C172614 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C172614 NCIT_P108 "Galidesivir Hydrochloride" @default.
- NCIT_C172614 NCIT_P208 "CL1406703" @default.
- NCIT_C172614 NCIT_P210 "222631-44-9" @default.
- NCIT_C172614 NCIT_P319 "1EL1K52SH1" @default.
- NCIT_C172614 NCIT_P322 "FDA" @default.
- NCIT_C172614 normalizedInformationContent "100" @default.
- NCIT_C172614 referenceCount "1" @default.
- NCIT_C172614 hasExactSynonym "BCX4430 Hydrochloride" @default.
- NCIT_C172614 hasExactSynonym "GALIDESIVIR HYDROCHLORIDE" @default.
- NCIT_C172614 hasExactSynonym "Galidesivir Hydrochloride" @default.
- NCIT_C172614 inSubset NCIT_C173381 @default.
- NCIT_C172614 inSubset NCIT_C173383 @default.
- NCIT_C172614 inSubset NCIT_C63923 @default.
- NCIT_C172614 type Class @default.
- NCIT_C172614 isDefinedBy ncit.owl @default.
- NCIT_C172614 label "Galidesivir Hydrochloride" @default.
- NCIT_C172614 subClassOf NCIT_C172614 @default.
- NCIT_C172614 subClassOf NCIT_C1908 @default.
- NCIT_C172614 subClassOf NCIT_C1909 @default.
- NCIT_C172614 subClassOf NCIT_C254 @default.
- NCIT_C172614 subClassOf NCIT_C281 @default.
- NCIT_C172614 subClassOf NCIT_C29575 @default.
- NCIT_C172614 subClassOf NCIT_C471 @default.