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- NCIT_C172633 IAO_0000115 "An orally bioavailable prodrug of EIDD-1931, the synthetic ribonucleoside derivative N4-hydroxycytidine and ribonucleoside analog, with potential antiviral activity against a variety of RNA viruses. Upon oral administration, molnupiravir, being a prodrug, is metabolized into its active form EIDD-1931 and converted into its triphosphate (TP) form. The TP form of EIDD-1931 is incorporated into RNA and inhibits the action of viral RNA-dependent RNA polymerase. This results in the termination of RNA transcription and decreases viral RNA production, and viral RNA replication." @default.
- NCIT_C172633 NCIT_A48 NCIT_C17998 @default.
- NCIT_C172633 NCIT_A48 NCIT_C49487 @default.
- NCIT_C172633 NCIT_A48 NCIT_C49488 @default.
- NCIT_C172633 NCIT_NHC0 "C172633" @default.
- NCIT_C172633 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C172633 NCIT_P108 "Molnupiravir" @default.
- NCIT_C172633 NCIT_P208 "CL1406746" @default.
- NCIT_C172633 NCIT_P210 "2349386-89-4" @default.
- NCIT_C172633 NCIT_P319 "YA84KI1VEW" @default.
- NCIT_C172633 NCIT_P322 "ACC/AHA" @default.
- NCIT_C172633 NCIT_P322 "FDA" @default.
- NCIT_C172633 normalizedInformationContent "100" @default.
- NCIT_C172633 referenceCount "1" @default.
- NCIT_C172633 hasExactSynonym "EIDD 2801" @default.
- NCIT_C172633 hasExactSynonym "EIDD-2801" @default.
- NCIT_C172633 hasExactSynonym "EIDD2801" @default.
- NCIT_C172633 hasExactSynonym "Lagevrio" @default.
- NCIT_C172633 hasExactSynonym "MK 4482" @default.
- NCIT_C172633 hasExactSynonym "MK-4482" @default.
- NCIT_C172633 hasExactSynonym "MK4482" @default.
- NCIT_C172633 hasExactSynonym "MOLNUPIRAVIR" @default.
- NCIT_C172633 hasExactSynonym "Molnupiravir" @default.
- NCIT_C172633 hasExactSynonym "N4-Hydroxycytidine, 5'-Isopropyl Ester" @default.
- NCIT_C172633 hasExactSynonym "SARS-CoV-2 antiviral agents: molnupiravir" @default.
- NCIT_C172633 hasExactSynonym "Uridine, 4-Oxime, 5'-(2-Methylpropanoate)" @default.
- NCIT_C172633 inSubset NCIT_C173381 @default.
- NCIT_C172633 inSubset NCIT_C173383 @default.
- NCIT_C172633 inSubset NCIT_C191200 @default.
- NCIT_C172633 inSubset NCIT_C191387 @default.
- NCIT_C172633 inSubset NCIT_C191404 @default.
- NCIT_C172633 inSubset NCIT_C191670 @default.
- NCIT_C172633 inSubset NCIT_C63923 @default.
- NCIT_C172633 type Class @default.
- NCIT_C172633 isDefinedBy ncit.owl @default.
- NCIT_C172633 label "Molnupiravir" @default.
- NCIT_C172633 subClassOf NCIT_C172633 @default.
- NCIT_C172633 subClassOf NCIT_C190794 @default.
- NCIT_C172633 subClassOf NCIT_C1908 @default.
- NCIT_C172633 subClassOf NCIT_C1909 @default.
- NCIT_C172633 subClassOf NCIT_C254 @default.
- NCIT_C172633 subClassOf NCIT_C281 @default.