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- NCIT_C17275 IAO_0000115 "Ubiquitous heterodimeric human Calcineurin is Ca(2+)/calmodulin-regulated protein phosphatase involved in many biologic activities as a modifier of phosphorylation status. Composed of widely expressed or tissue-restricted 55-60-kDa calmodulin-binding catalytic subunit (PPP Phosphatase/PP-2B Family) and conserved 19-kD Ca(2+)-sensitive regulatory subunit, Calcineurin appears to regulate glycolytic metabolism, nuclear translocation of NFATC1 transcription factor, sperm motility, and dopaminergic signal transduction and NMDA receptor-dependent synaptic plasticity. (NCI)" @default.
- NCIT_C17275 NCIT_NHC0 "C17275" @default.
- NCIT_C17275 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C17275 NCIT_P106 "Enzyme" @default.
- NCIT_C17275 NCIT_P107 "Calcineurin" @default.
- NCIT_C17275 NCIT_P108 "Calcineurin" @default.
- NCIT_C17275 NCIT_P207 "C0054450" @default.
- NCIT_C17275 NCIT_P322 "CTRP" @default.
- NCIT_C17275 NCIT_P366 "Calcineurin" @default.
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- NCIT_C17275 referenceCount "6" @default.
- NCIT_C17275 hasExactSynonym "Calcineurin" @default.
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- NCIT_C17275 type Class @default.
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- NCIT_C17275 label "Calcineurin" @default.
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