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Matches in Ubergraph for { <http://purl.obolibrary.org/obo/NCIT_C17279> ?p ?o ?g. }

• NCIT_C17279 IAO_0000115 "B-cell receptor CD22 (847 aa, ~95 kDa) is encoded by the human CD22 gene. This protein is involved in B-cell/B-cell interactions and downstream signaling." @default.
• NCIT_C17279 NCIT_A32 NCIT_C268 @default.
• NCIT_C17279 NCIT_NHC0 "C17279" @default.
• NCIT_C17279 NCIT_P100 "107266" @default.
• NCIT_C17279 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
• NCIT_C17279 NCIT_P106 "Immunologic Factor" @default.
• NCIT_C17279 NCIT_P107 "B-Cell Receptor CD22" @default.
• NCIT_C17279 NCIT_P108 "B-Cell Receptor CD22" @default.
• NCIT_C17279 NCIT_P207 "C1505685" @default.
• NCIT_C17279 NCIT_P322 "CTRP" @default.
• NCIT_C17279 NCIT_P322 "GDC" @default.
• NCIT_C17279 NCIT_P366 "CD22_Antigen" @default.
• NCIT_C17279 NCIT_P375 "CD22" @default.
• NCIT_C17279 NCIT_P93 "P20273" @default.
• NCIT_C17279 NCIT_P98 "The CD22 gene is expressed in pro-B cells as a cytoplasmic protein and later as a cell surface protein, persisting until they differentiate into plasma cells. CD22 antigen is a glycoprotein heterodimer with two subunits from separate precursor molecules that arise by differential RNA processing of the same gene. The larger subunit is composed of an extracellular portion of seven Ig domains and a smaller subunit of five Ig domains. Structurally related to MAG, NCAM, and CEA, CD22 participates in adhesion between B-cells and other cell types. Conserved ITIM motifs in inhibitory receptors are sites for phosphorylation by a SRC kinase and dephosphorylation by tyrosine phosphatase SHP1 or inositol phosphatase SHIP, transducing signals to distinct pathways. CD22 ITIMs interact with SHP1 and oppose activation mediated by the B-cell receptor. CD22 is a negative regulator of antigen receptor signaling." @default.
• NCIT_C17279 NCIT_R131 NCIT_C17132 @default.
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• NCIT_C17279 NCIT_R50 NCIT_C13671 @default.
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• NCIT_C17279 NCIT_R53 NCIT_C19986 @default.
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• NCIT_C17279 NCIT_R53 NCIT_C20480 @default.
• NCIT_C17279 NCIT_R53 NCIT_C41514 @default.
• NCIT_C17279 NCIT_R54 NCIT_C16612 @default.
• NCIT_C17279 NCIT_R54 NCIT_C20988 @default.
• NCIT_C17279 NCIT_R54 NCIT_C20990 @default.
• NCIT_C17279 NCIT_R54 NCIT_C21295 @default.
• NCIT_C17279 normalizedInformationContent "100" @default.
• NCIT_C17279 referenceCount "1" @default.
• NCIT_C17279 hasExactSynonym "B-Cell Antigen CD22" @default.
• NCIT_C17279 hasExactSynonym "B-Cell Receptor CD22" @default.
• NCIT_C17279 hasExactSynonym "B-Lymphocyte Cell Adhesion Molecule" @default.
• NCIT_C17279 hasExactSynonym "BL-CAM" @default.
• NCIT_C17279 hasExactSynonym "CD22 Antigen" @default.
• NCIT_C17279 hasExactSynonym "CD22" @default.
• NCIT_C17279 hasExactSynonym "Lyb8" @default.
• NCIT_C17279 hasExactSynonym "Sialic Acid-Binding Ig-Like Lectin 2" @default.
• NCIT_C17279 hasExactSynonym "Sialic Acid-Binding Immunoglobulin-Like Lectin 2" @default.
• NCIT_C17279 hasExactSynonym "Siglec-2" @default.
• NCIT_C17279 hasExactSynonym "T-Cell Surface Antigen Leu-14" @default.
• NCIT_C17279 inSubset NCIT_C116977 @default.
• NCIT_C17279 inSubset NCIT_C142799 @default.
• NCIT_C17279 inSubset NCIT_C142800 @default.
• NCIT_C17279 inSubset NCIT_C157711 @default.
• NCIT_C17279 inSubset NCIT_C177537 @default.
• NCIT_C17279 type Class @default.
• NCIT_C17279 isDefinedBy ncit.owl @default.
• NCIT_C17279 label "B-Cell Receptor CD22" @default.
• NCIT_C17279 subClassOf NCIT_C16393 @default.
• NCIT_C17279 subClassOf NCIT_C17021 @default.
• NCIT_C17279 subClassOf NCIT_C17279 @default.
• NCIT_C17279 subClassOf NCIT_C17728 @default.
• NCIT_C17279 subClassOf NCIT_C20027 @default.
• NCIT_C17279 subClassOf NCIT_C26548 @default.

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