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NCIT_C17281 IAO_0000115 "Tumor necrosis factor receptor superfamily member 5 (277 aa, ~31 kDa) is encoded by the human CD40 gene. This protein is involved in the positive regulation of immunoglobulin secretion." @default.
NCIT_C17281 NCIT_NHC0 "C17281" @default.
NCIT_C17281 NCIT_P100 "109535" @default.
NCIT_C17281 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
NCIT_C17281 NCIT_P106 "Receptor" @default.
NCIT_C17281 NCIT_P107 "Tumor Necrosis Factor Receptor Superfamily Member 5" @default.
NCIT_C17281 NCIT_P108 "Tumor Necrosis Factor Receptor Superfamily Member 5" @default.
NCIT_C17281 NCIT_P207 "C0054959" @default.
NCIT_C17281 NCIT_P322 "CTRP" @default.
NCIT_C17281 NCIT_P366 "CD40L_Receptor" @default.
NCIT_C17281 NCIT_P93 "P25942" @default.
NCIT_C17281 NCIT_P98 "Related to NGFR, TNFR-alpha, and CD27, CD40 is a 50 kD glycophosphoprotein homodimer expressed on mature B-cells, but not on plasma cells, that plays an important role in B-cell development and activation. These CD40 homologies imply that its ligand may be a soluble factor and that CD40 is a member of the cytokine receptor family. CD40/CD40-ligand interactions play a critical role in the activation of humoral and cell-mediated immune responses. CD40-dependent activation of B-cells is important for generation of memory B-cells within germinal centers. (OMIM)" @default.
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