Matches in Ubergraph for { <http://purl.obolibrary.org/obo/NCIT_C172914> ?p ?o ?g. }
Showing items 1 to 37 of
37
with 100 items per page.
- NCIT_C172914 IAO_0000115 "An off-the-shelf (OTS) cancer vaccine comprised of a genetically engineered, replication-deficient gorilla-derived adenovirus encoding human papillomavirus (HPV) types 16 and 18 E6/E7 antigens, with potential immunostimulating and antineoplastic activities. Upon administration of gorilla-derived adenovirus expressing HPV-16/18 E6/E7 vaccine PRGN-2009, the adenovirus infects and expresses the HPV-16/18 E6/E7 proteins. The expressed proteins stimulate the host immune system to produce antigen-specific neutralizing antibodies and to mount a cytotoxic T-lymphocyte (CTL) response against tumor cells expressing HPV-16/18 E6/E7 antigens, thereby inducing tumor cell lysis. HPV oncoproteins play a key role in the development of cervical intraepithelial neoplasia (CIN) and cervical carcinoma." @default.
- NCIT_C172914 NCIT_A7 NCIT_C1179 @default.
- NCIT_C172914 NCIT_A7 NCIT_C1397 @default.
- NCIT_C172914 NCIT_A7 NCIT_C17520 @default.
- NCIT_C172914 NCIT_A7 NCIT_C17674 @default.
- NCIT_C172914 NCIT_NHC0 "C172914" @default.
- NCIT_C172914 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C172914 NCIT_P107 "Gorilla-derived Adenovirus-expressing HPV-16/18 E6/E7 Vaccine" @default.
- NCIT_C172914 NCIT_P108 "Gorilla-derived Adenovirus-expressing HPV-16/18 E6/E7 Vaccine" @default.
- NCIT_C172914 NCIT_P208 "CL1406936" @default.
- NCIT_C172914 NCIT_P322 "CTRP" @default.
- NCIT_C172914 NCIT_P329 "802037" @default.
- NCIT_C172914 NCIT_P330 "802037" @default.
- NCIT_C172914 NCIT_P366 "Adenovirus_Encoding_Recombinant_Human_Endostatin" @default.
- NCIT_C172914 NCIT_P399 "802037" @default.
- NCIT_C172914 normalizedInformationContent "100" @default.
- NCIT_C172914 referenceCount "1" @default.
- NCIT_C172914 hasExactSynonym "Gorilla-derived Adenovirus-expressing HPV-16/18 E6/E7 Vaccine" @default.
- NCIT_C172914 hasExactSynonym "HPV Vaccine PRGN-2009" @default.
- NCIT_C172914 hasExactSynonym "PRGN 2009" @default.
- NCIT_C172914 hasExactSynonym "PRGN-2009" @default.
- NCIT_C172914 hasExactSynonym "PRGN2009" @default.
- NCIT_C172914 inSubset NCIT_C116977 @default.
- NCIT_C172914 inSubset NCIT_C116978 @default.
- NCIT_C172914 inSubset NCIT_C128784 @default.
- NCIT_C172914 inSubset NCIT_C176424 @default.
- NCIT_C172914 type Class @default.
- NCIT_C172914 isDefinedBy ncit.owl @default.
- NCIT_C172914 label "Gorilla-derived Adenovirus-expressing HPV-16/18 E6/E7 Vaccine" @default.
- NCIT_C172914 subClassOf NCIT_C129821 @default.
- NCIT_C172914 subClassOf NCIT_C172914 @default.
- NCIT_C172914 subClassOf NCIT_C1908 @default.
- NCIT_C172914 subClassOf NCIT_C1909 @default.
- NCIT_C172914 subClassOf NCIT_C1962 @default.
- NCIT_C172914 subClassOf NCIT_C274 @default.
- NCIT_C172914 subClassOf NCIT_C307 @default.
- NCIT_C172914 subClassOf NCIT_C61199 @default.