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- NCIT_C173371 IAO_0000115 "A fusion protein composed of human interleukin-12 (IL-12) fused to a Fc fragment, with potential immunomodulatory and antineoplastic activities. Upon administration of IL-12-Fc fusion protein DF6002, the IL-12 moiety binds to the IL-12 receptor. This may activate the immune system by promoting the secretion of interferon-gamma, activating natural killer cells (NKs), and inducing cytotoxic T-lymphocyte (CTL) responses, which may result in both decreased tumor cell proliferation and enhanced immune-mediated destruction of tumor cells." @default.
- NCIT_C173371 NCIT_A32 NCIT_C1909 @default.
- NCIT_C173371 NCIT_A7 NCIT_C38915 @default.
- NCIT_C173371 NCIT_NHC0 "C173371" @default.
- NCIT_C173371 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C173371 NCIT_P107 "Interleukin-12-Fc Fusion Protein DF6002" @default.
- NCIT_C173371 NCIT_P108 "Interleukin-12-Fc Fusion Protein DF6002" @default.
- NCIT_C173371 NCIT_P208 "CL1407203" @default.
- NCIT_C173371 NCIT_P322 "CTRP" @default.
- NCIT_C173371 NCIT_P322 "GDC" @default.
- NCIT_C173371 NCIT_P329 "801838" @default.
- NCIT_C173371 NCIT_P330 "801838" @default.
- NCIT_C173371 NCIT_P375 "Interleukin-12-Fc Fusion Protein DF6002" @default.
- NCIT_C173371 NCIT_P399 "801838" @default.
- NCIT_C173371 normalizedInformationContent "100" @default.
- NCIT_C173371 referenceCount "1" @default.
- NCIT_C173371 hasExactSynonym "DF 6002" @default.
- NCIT_C173371 hasExactSynonym "DF-6002" @default.
- NCIT_C173371 hasExactSynonym "DF6002" @default.
- NCIT_C173371 hasExactSynonym "IL-12-Fc Fusion Protein DF6002" @default.
- NCIT_C173371 hasExactSynonym "Interleukin-12-Fc Fusion Protein DF6002" @default.
- NCIT_C173371 inSubset NCIT_C116977 @default.
- NCIT_C173371 inSubset NCIT_C116978 @default.
- NCIT_C173371 inSubset NCIT_C128784 @default.
- NCIT_C173371 inSubset NCIT_C157711 @default.
- NCIT_C173371 inSubset NCIT_C157712 @default.
- NCIT_C173371 inSubset NCIT_C176424 @default.
- NCIT_C173371 inSubset NCIT_C177537 @default.
- NCIT_C173371 type Class @default.
- NCIT_C173371 isDefinedBy ncit.owl @default.
- NCIT_C173371 label "Interleukin-12-Fc Fusion Protein DF6002" @default.
- NCIT_C173371 subClassOf NCIT_C129820 @default.
- NCIT_C173371 subClassOf NCIT_C173371 @default.
- NCIT_C173371 subClassOf NCIT_C1908 @default.
- NCIT_C173371 subClassOf NCIT_C1909 @default.
- NCIT_C173371 subClassOf NCIT_C274 @default.
- NCIT_C173371 subClassOf NCIT_C308 @default.