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- NCIT_C173512 IAO_0000115 "A second generation, synthetic, low-molecular-weight heparin (LMWH) with anticoagulant activity. Derived, after depolymerisation and fractionation, from medical-grade porcine unfractionated heparin (UFH), bemiparin has an average molecular weight of 3,600 daltons and has a higher anti-factor Xa/anti-factor IIa ratio (8:1) than first-generation LMWHs. This anticoagulant binds to antithrombin III, thereby enhancing the inactivation of activated factor X (Factor Xa) and, to a lesser extent, activated factor II (Factor IIa). Compared to unfractionated heparins, the use of bemiparin is associated with lower incidences of major bleeding, osteoporosis, and heparin-induced thrombocytopenia. Bemiparin also promotes a greater release of tissue factor pathway inhibitor than UFH or dalteparin." @default.
- NCIT_C173512 NCIT_A5 NCIT_C53400 @default.
- NCIT_C173512 NCIT_NHC0 "C173512" @default.
- NCIT_C173512 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C173512 NCIT_P108 "Bemiparin" @default.
- NCIT_C173512 NCIT_P208 "CL1407473" @default.
- NCIT_C173512 NCIT_P319 "PUE0TO3XDR" @default.
- NCIT_C173512 NCIT_P322 "FDA" @default.
- NCIT_C173512 normalizedInformationContent "100" @default.
- NCIT_C173512 referenceCount "1" @default.
- NCIT_C173512 hasExactSynonym "BEMIPARIN" @default.
- NCIT_C173512 hasExactSynonym "Bemiparin" @default.
- NCIT_C173512 inSubset NCIT_C173381 @default.
- NCIT_C173512 inSubset NCIT_C173383 @default.
- NCIT_C173512 inSubset NCIT_C63923 @default.
- NCIT_C173512 type Class @default.
- NCIT_C173512 isDefinedBy ncit.owl @default.
- NCIT_C173512 label "Bemiparin" @default.
- NCIT_C173512 subClassOf NCIT_C173512 @default.
- NCIT_C173512 subClassOf NCIT_C1908 @default.
- NCIT_C173512 subClassOf NCIT_C1909 @default.
- NCIT_C173512 subClassOf NCIT_C2578 @default.
- NCIT_C173512 subClassOf NCIT_C263 @default.
- NCIT_C173512 subClassOf NCIT_C78275 @default.