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- NCIT_C173664 IAO_0000115 "A mimetic of the enzyme superoxide dismutase (SOD) that may potentially be used to increase the anti-cancer efficacy of stereotactic body radiation therapy (SBRT). Upon administration, rucosopasem manganese may mimic native SODs and catalyze the formation of molecular oxygen and hydrogen peroxide from the burst of superoxide anion present in the irradiated tissues upon radiation. As hydrogen peroxide is less toxic than superoxide to normal tissues, but more toxic to cancer cells, this may increase the anti-cancer efficacy of SBRT and decrease its damage to normal tissues." @default.
- NCIT_C173664 NCIT_A32 NCIT_C1909 @default.
- NCIT_C173664 NCIT_NHC0 "C173664" @default.
- NCIT_C173664 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C173664 NCIT_P107 "Superoxide Dismutase Mimetic GC4711" @default.
- NCIT_C173664 NCIT_P108 "Rucosopasem Manganese" @default.
- NCIT_C173664 NCIT_P208 "CL1407386" @default.
- NCIT_C173664 NCIT_P210 "2248030-85-3" @default.
- NCIT_C173664 NCIT_P319 "FW5T90VM32" @default.
- NCIT_C173664 NCIT_P322 "CTRP" @default.
- NCIT_C173664 NCIT_P322 "FDA" @default.
- NCIT_C173664 NCIT_P322 "GDC" @default.
- NCIT_C173664 NCIT_P329 "802254" @default.
- NCIT_C173664 NCIT_P330 "802254" @default.
- NCIT_C173664 NCIT_P375 "Superoxide Dismutase Mimetic GC4711" @default.
- NCIT_C173664 NCIT_P399 "802254" @default.
- NCIT_C173664 normalizedInformationContent "100" @default.
- NCIT_C173664 referenceCount "1" @default.
- NCIT_C173664 hasExactSynonym "Avasopasem Manganese Dipropionate" @default.
- NCIT_C173664 hasExactSynonym "GC 4711" @default.
- NCIT_C173664 hasExactSynonym "GC-4711" @default.
- NCIT_C173664 hasExactSynonym "GC4711" @default.
- NCIT_C173664 hasExactSynonym "RUCOSOPASEM MANGANESE" @default.
- NCIT_C173664 hasExactSynonym "Rucosopasem Manganese" @default.
- NCIT_C173664 hasExactSynonym "SOD Mimetic GC4711" @default.
- NCIT_C173664 hasExactSynonym "Superoxide Dismutase Mimetic GC4711" @default.
- NCIT_C173664 inSubset NCIT_C116977 @default.
- NCIT_C173664 inSubset NCIT_C116978 @default.
- NCIT_C173664 inSubset NCIT_C128784 @default.
- NCIT_C173664 inSubset NCIT_C157711 @default.
- NCIT_C173664 inSubset NCIT_C157712 @default.
- NCIT_C173664 inSubset NCIT_C176424 @default.
- NCIT_C173664 inSubset NCIT_C177537 @default.
- NCIT_C173664 inSubset NCIT_C63923 @default.
- NCIT_C173664 type Class @default.
- NCIT_C173664 isDefinedBy ncit.owl @default.
- NCIT_C173664 label "Rucosopasem Manganese" @default.
- NCIT_C173664 subClassOf NCIT_C173664 @default.
- NCIT_C173664 subClassOf NCIT_C1908 @default.
- NCIT_C173664 subClassOf NCIT_C1909 @default.
- NCIT_C173664 subClassOf NCIT_C26170 @default.
- NCIT_C173664 subClassOf NCIT_C275 @default.