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- NCIT_C173850 IAO_0000115 "A recombinant protein-based vaccine composed of a recombinant spike (S) protein receptor-binding domain (RBD)-dimer, produced in Chinese hamster ovary (CHO) cells, of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), with potential immunomodulating and anti-coronavirus disease 2019 (COVID-19) activities. Upon intramuscular administration of the recombinant S-protein RBD-dimer SARS-CoV-2 vaccine, the S protein RBD-dimer activates the immune system to create anti-SARS-CoV-2 S protein antibodies. The antibodies recognize and neutralize the S protein and kill SARS-CoV-2. This prevents SARS-CoV-2 infection. S-protein, usually found on the surface of SARS-CoV-2, plays an essential role in the infection pathway of the SARS-CoV-2 virus. The dimeric form of SARS-CoV-2 RBD may increase its immunogenicity." @default.
- NCIT_C173850 NCIT_NHC0 "C173850" @default.
- NCIT_C173850 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C173850 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C173850 NCIT_P108 "Recombinant Spike-protein Receptor-binding Domain-dimer SARS-CoV-2 Vaccine" @default.
- NCIT_C173850 NCIT_P208 "CL1407646" @default.
- NCIT_C173850 NCIT_R124 NCIT_C17828 @default.
- NCIT_C173850 NCIT_R124 NCIT_C17930 @default.
- NCIT_C173850 NCIT_R124 NCIT_C17937 @default.
- NCIT_C173850 NCIT_R124 NCIT_C18839 @default.
- NCIT_C173850 NCIT_R124 NCIT_C21124 @default.
- NCIT_C173850 NCIT_R124 NCIT_C45548 @default.
- NCIT_C173850 normalizedInformationContent "100" @default.
- NCIT_C173850 referenceCount "1" @default.
- NCIT_C173850 hasExactSynonym "Recombinant S-protein RBD-dimer SARS-CoV-2 Vaccine" @default.
- NCIT_C173850 hasExactSynonym "Recombinant Spike-protein RBD-dimer Coronavirus Vaccine" @default.
- NCIT_C173850 hasExactSynonym "Recombinant Spike-protein Receptor-binding Domain-dimer SARS-CoV-2 Vaccine" @default.
- NCIT_C173850 inSubset NCIT_C173381 @default.
- NCIT_C173850 inSubset NCIT_C173383 @default.
- NCIT_C173850 type Class @default.
- NCIT_C173850 isDefinedBy ncit.owl @default.
- NCIT_C173850 label "Recombinant Spike-protein Receptor-binding Domain-dimer SARS-CoV-2 Vaccine" @default.
- NCIT_C173850 subClassOf NCIT_C173023 @default.
- NCIT_C173850 subClassOf NCIT_C173850 @default.
- NCIT_C173850 subClassOf NCIT_C1752 @default.
- NCIT_C173850 subClassOf NCIT_C1908 @default.
- NCIT_C173850 subClassOf NCIT_C1909 @default.
- NCIT_C173850 subClassOf NCIT_C307 @default.
- NCIT_C173850 subClassOf NCIT_C308 @default.
- NCIT_C173850 subClassOf NCIT_C923 @default.