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- NCIT_C173851 IAO_0000115 "A vaccine consisting of a lipid nanoparticle (LNP) encapsulating a messenger RNA (mRNA) encoding the full-length spike (S) protein of severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2), with potential immunizing activity against SARS-CoV-2. Upon intramuscular administration of zorecimeran, the LNP binds to the plasma membrane of cells and releases the mRNA into the cells. The mRNA is then translated by ribosomes to produce the SARS-CoV-2 S protein. This may activate both humoral and cellular immune responses which may result in protection against SARS-CoV-2 infection. S-protein, usually found on the surface of SARS-CoV-2, plays an essential role in the infection pathway of the SARS-CoV-2 virus." @default.
- NCIT_C173851 NCIT_NHC0 "C173851" @default.
- NCIT_C173851 NCIT_P106 "Nucleic Acid, Nucleoside, or Nucleotide" @default.
- NCIT_C173851 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C173851 NCIT_P108 "Zorecimeran" @default.
- NCIT_C173851 NCIT_P208 "CL1407645" @default.
- NCIT_C173851 NCIT_P210 "2432957-15-6" @default.
- NCIT_C173851 NCIT_P319 "5TP24STD1S" @default.
- NCIT_C173851 NCIT_P322 "FDA" @default.
- NCIT_C173851 normalizedInformationContent "100" @default.
- NCIT_C173851 referenceCount "1" @default.
- NCIT_C173851 hasExactSynonym "COVID-19 mRNA Vaccine CVnCoV" @default.
- NCIT_C173851 hasExactSynonym "CV 07050101" @default.
- NCIT_C173851 hasExactSynonym "CV-07050101" @default.
- NCIT_C173851 hasExactSynonym "CV07050101" @default.
- NCIT_C173851 hasExactSynonym "CVnCoV Vaccine" @default.
- NCIT_C173851 hasExactSynonym "CVnCoV" @default.
- NCIT_C173851 hasExactSynonym "LNP-encapsulated SARS-CoV-2 mRNA Vaccine CVnCoV" @default.
- NCIT_C173851 hasExactSynonym "ZORECIMERAN" @default.
- NCIT_C173851 hasExactSynonym "Zorecimeran" @default.
- NCIT_C173851 inSubset NCIT_C173381 @default.
- NCIT_C173851 inSubset NCIT_C173383 @default.
- NCIT_C173851 inSubset NCIT_C63923 @default.
- NCIT_C173851 type Class @default.
- NCIT_C173851 isDefinedBy ncit.owl @default.
- NCIT_C173851 label "Zorecimeran" @default.
- NCIT_C173851 subClassOf NCIT_C172787 @default.
- NCIT_C173851 subClassOf NCIT_C173023 @default.
- NCIT_C173851 subClassOf NCIT_C173851 @default.
- NCIT_C173851 subClassOf NCIT_C181140 @default.
- NCIT_C173851 subClassOf NCIT_C1908 @default.
- NCIT_C173851 subClassOf NCIT_C1909 @default.
- NCIT_C173851 subClassOf NCIT_C307 @default.
- NCIT_C173851 subClassOf NCIT_C308 @default.
- NCIT_C173851 subClassOf NCIT_C923 @default.