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- NCIT_C173969 IAO_0000115 "A monoclonal antibody against CD25 (IL-2R alpha), with potential antineoplastic activity. Upon administration, vopikitug targets and binds to CD25 expressed on tumor-infiltrating regulatory T (Treg) cells. This may deplete Treg cells and prevent immunosuppression, thereby enhancing anti-tumor immune responses. CD25, the alpha chain of the interleukin (IL)-2 receptor, is highly expressed on Treg cells but not on effector T (Teff) cells in tumors." @default.
- NCIT_C173969 NCIT_A32 NCIT_C1909 @default.
- NCIT_C173969 NCIT_NHC0 "C173969" @default.
- NCIT_C173969 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C173969 NCIT_P107 "Vopikitug" @default.
- NCIT_C173969 NCIT_P108 "Vopikitug" @default.
- NCIT_C173969 NCIT_P208 "CL1407855" @default.
- NCIT_C173969 NCIT_P210 "2733581-99-0" @default.
- NCIT_C173969 NCIT_P319 "HV8TQI2IKP" @default.
- NCIT_C173969 NCIT_P322 "CTRP" @default.
- NCIT_C173969 NCIT_P322 "FDA" @default.
- NCIT_C173969 NCIT_P322 "GDC" @default.
- NCIT_C173969 NCIT_P329 "802183" @default.
- NCIT_C173969 NCIT_P330 "802183" @default.
- NCIT_C173969 NCIT_P375 "Anti-CD25 Monoclonal Antibody RO7296682" @default.
- NCIT_C173969 NCIT_P399 "802183" @default.
- NCIT_C173969 NCIT_R124 NCIT_C17710 @default.
- NCIT_C173969 NCIT_R124 NCIT_C17828 @default.
- NCIT_C173969 NCIT_R124 NCIT_C18219 @default.
- NCIT_C173969 NCIT_R124 NCIT_C19986 @default.
- NCIT_C173969 NCIT_R124 NCIT_C40474 @default.
- NCIT_C173969 normalizedInformationContent "100" @default.
- NCIT_C173969 referenceCount "1" @default.
- NCIT_C173969 hasExactSynonym "Anti-CD25 Monoclonal Antibody RG6292" @default.
- NCIT_C173969 hasExactSynonym "Anti-CD25 Monoclonal Antibody RO7296682" @default.
- NCIT_C173969 hasExactSynonym "RG 6292" @default.
- NCIT_C173969 hasExactSynonym "RG-6292" @default.
- NCIT_C173969 hasExactSynonym "RG6292" @default.
- NCIT_C173969 hasExactSynonym "RO 7296682" @default.
- NCIT_C173969 hasExactSynonym "RO-7296682" @default.
- NCIT_C173969 hasExactSynonym "RO7296682" @default.
- NCIT_C173969 hasExactSynonym "T-regulatory Cell-depleting Antibody RO7296682" @default.
- NCIT_C173969 hasExactSynonym "VOPIKITUG" @default.
- NCIT_C173969 hasExactSynonym "Vopikitug" @default.
- NCIT_C173969 inSubset NCIT_C116977 @default.
- NCIT_C173969 inSubset NCIT_C116978 @default.
- NCIT_C173969 inSubset NCIT_C128784 @default.
- NCIT_C173969 inSubset NCIT_C157711 @default.
- NCIT_C173969 inSubset NCIT_C157712 @default.
- NCIT_C173969 inSubset NCIT_C176424 @default.
- NCIT_C173969 inSubset NCIT_C177537 @default.
- NCIT_C173969 inSubset NCIT_C63923 @default.
- NCIT_C173969 type Class @default.
- NCIT_C173969 isDefinedBy ncit.owl @default.
- NCIT_C173969 label "Vopikitug" @default.
- NCIT_C173969 subClassOf NCIT_C129821 @default.
- NCIT_C173969 subClassOf NCIT_C129822 @default.
- NCIT_C173969 subClassOf NCIT_C173969 @default.
- NCIT_C173969 subClassOf NCIT_C1908 @default.
- NCIT_C173969 subClassOf NCIT_C1909 @default.
- NCIT_C173969 subClassOf NCIT_C20401 @default.
- NCIT_C173969 subClassOf NCIT_C274 @default.
- NCIT_C173969 subClassOf NCIT_C307 @default.
- NCIT_C173969 subClassOf NCIT_C308 @default.
- NCIT_C173969 subClassOf NCIT_C75525 @default.