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- NCIT_C174208 IAO_0000115 "An orally bioavailable inhibitor of the fibroblast growth factor receptor 2 (FGFR2), with potential antineoplastic activity. Upon oral administration, lirafugratinib binds to and inhibits FGFR2, which results in the inhibition of FGFR2-mediated signal transduction pathways. This inhibits the proliferation of FGFR2-overexpressing tumor cells. FGFR2, a receptor tyrosine kinase upregulated in many tumor cell types, plays a key role in cellular proliferation, migration and survival." @default.
- NCIT_C174208 NCIT_A32 NCIT_C1909 @default.
- NCIT_C174208 NCIT_A7 NCIT_C17411 @default.
- NCIT_C174208 NCIT_NHC0 "C174208" @default.
- NCIT_C174208 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C174208 NCIT_P107 "Lirafugratinib" @default.
- NCIT_C174208 NCIT_P108 "Lirafugratinib" @default.
- NCIT_C174208 NCIT_P208 "CL1411775" @default.
- NCIT_C174208 NCIT_P210 "2549174-42-5" @default.
- NCIT_C174208 NCIT_P319 "7HY6IMH87S" @default.
- NCIT_C174208 NCIT_P322 "CTRP" @default.
- NCIT_C174208 NCIT_P322 "FDA" @default.
- NCIT_C174208 NCIT_P322 "GDC" @default.
- NCIT_C174208 NCIT_P329 "803114" @default.
- NCIT_C174208 NCIT_P330 "803114" @default.
- NCIT_C174208 NCIT_P375 "FGFR2 Inhibitor RLY-4008" @default.
- NCIT_C174208 NCIT_P399 "803114" @default.
- NCIT_C174208 normalizedInformationContent "100" @default.
- NCIT_C174208 referenceCount "1" @default.
- NCIT_C174208 hasExactSynonym "FGFR2 Inhibitor RLY-4008" @default.
- NCIT_C174208 hasExactSynonym "Fibroblast Growth Factor Receptor 2 Inhibitor RLY-4008" @default.
- NCIT_C174208 hasExactSynonym "LIRAFUGRATINIB" @default.
- NCIT_C174208 hasExactSynonym "Lirafugratinib" @default.
- NCIT_C174208 hasExactSynonym "RLY 4008" @default.
- NCIT_C174208 hasExactSynonym "RLY-4008" @default.
- NCIT_C174208 hasExactSynonym "RLY4008" @default.
- NCIT_C174208 inSubset NCIT_C116977 @default.
- NCIT_C174208 inSubset NCIT_C116978 @default.
- NCIT_C174208 inSubset NCIT_C128784 @default.
- NCIT_C174208 inSubset NCIT_C157711 @default.
- NCIT_C174208 inSubset NCIT_C157712 @default.
- NCIT_C174208 inSubset NCIT_C176424 @default.
- NCIT_C174208 inSubset NCIT_C177537 @default.
- NCIT_C174208 inSubset NCIT_C63923 @default.
- NCIT_C174208 type Class @default.
- NCIT_C174208 isDefinedBy ncit.owl @default.
- NCIT_C174208 label "Lirafugratinib" @default.
- NCIT_C174208 subClassOf NCIT_C129824 @default.
- NCIT_C174208 subClassOf NCIT_C129825 @default.
- NCIT_C174208 subClassOf NCIT_C1404 @default.
- NCIT_C174208 subClassOf NCIT_C155727 @default.
- NCIT_C174208 subClassOf NCIT_C163758 @default.
- NCIT_C174208 subClassOf NCIT_C164035 @default.
- NCIT_C174208 subClassOf NCIT_C174208 @default.
- NCIT_C174208 subClassOf NCIT_C1908 @default.
- NCIT_C174208 subClassOf NCIT_C1909 @default.
- NCIT_C174208 subClassOf NCIT_C1967 @default.
- NCIT_C174208 subClassOf NCIT_C2189 @default.
- NCIT_C174208 subClassOf NCIT_C274 @default.
- NCIT_C174208 subClassOf NCIT_C471 @default.