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- NCIT_C174420 IAO_0000115 "A preparation of T-lymphocytes that have been genetically modified and transduced with a lentiviral vector expressing a chimeric antigen receptor (CAR) targeting the tumor-associated antigen (TAA) CD4 and containing, as of yet undisclosed co-stimulatory signaling domains, with potential immunostimulating and antineoplastic activities. Upon administration, anti-CD4 CAR T-cells target and bind to CD4-expressing tumor cells, thereby inducing selective toxicity in CD4-expressing tumor cells. CD4 antigen is expressed in CD4-positive T cell lymphomas." @default.
- NCIT_C174420 NCIT_NHC0 "C174420" @default.
- NCIT_C174420 NCIT_P106 "Cell" @default.
- NCIT_C174420 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C174420 NCIT_P107 "Anti-CD4 CAR T-cells" @default.
- NCIT_C174420 NCIT_P108 "Anti-CD4 CAR T-cells" @default.
- NCIT_C174420 NCIT_P208 "CL1411978" @default.
- NCIT_C174420 NCIT_P322 "CTRP" @default.
- NCIT_C174420 NCIT_P329 "802265" @default.
- NCIT_C174420 NCIT_P330 "802265" @default.
- NCIT_C174420 NCIT_P399 "802265" @default.
- NCIT_C174420 normalizedInformationContent "100" @default.
- NCIT_C174420 referenceCount "1" @default.
- NCIT_C174420 hasExactSynonym "Anti-CD4 CAR T-cells" @default.
- NCIT_C174420 hasExactSynonym "CD4 CAR T Cells" @default.
- NCIT_C174420 hasExactSynonym "CD4-specific CAR T Cells" @default.
- NCIT_C174420 inSubset NCIT_C116977 @default.
- NCIT_C174420 inSubset NCIT_C116978 @default.
- NCIT_C174420 inSubset NCIT_C128784 @default.
- NCIT_C174420 inSubset NCIT_C176424 @default.
- NCIT_C174420 type Class @default.
- NCIT_C174420 isDefinedBy ncit.owl @default.
- NCIT_C174420 label "Anti-CD4 CAR T-cells" @default.
- NCIT_C174420 subClassOf NCIT_C129820 @default.
- NCIT_C174420 subClassOf NCIT_C129821 @default.
- NCIT_C174420 subClassOf NCIT_C129826 @default.
- NCIT_C174420 subClassOf NCIT_C142078 @default.
- NCIT_C174420 subClassOf NCIT_C174420 @default.
- NCIT_C174420 subClassOf NCIT_C1908 @default.
- NCIT_C174420 subClassOf NCIT_C1909 @default.
- NCIT_C174420 subClassOf NCIT_C274 @default.
- NCIT_C174420 subClassOf NCIT_C28676 @default.
- NCIT_C174420 subClassOf NCIT_C307 @default.
- NCIT_C174420 subClassOf NCIT_C308 @default.