Matches in Ubergraph for { <http://purl.obolibrary.org/obo/NCIT_C17478> ?p ?o ?g. }
- NCIT_C17478 IAO_0000115 "Catenin beta-1 (781 aa, ~85 kDa) is encoded by the human CTNNB1 gene. This protein is involved in Wnt signaling, adherens junction structure, and the regulation of cell growth." @default.
- NCIT_C17478 NCIT_A33 NCIT_C51944 @default.
- NCIT_C17478 NCIT_NHC0 "C17478" @default.
- NCIT_C17478 NCIT_P100 "116806" @default.
- NCIT_C17478 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C17478 NCIT_P107 "Catenin Beta-1" @default.
- NCIT_C17478 NCIT_P108 "Catenin Beta-1" @default.
- NCIT_C17478 NCIT_P207 "C1531189" @default.
- NCIT_C17478 NCIT_P322 "CTRP" @default.
- NCIT_C17478 NCIT_P322 "PCDC" @default.
- NCIT_C17478 NCIT_P366 "Beta_Catenin" @default.
- NCIT_C17478 NCIT_P93 "P35222" @default.
- NCIT_C17478 NCIT_P98 "Beta-catenin is an adherens junction protein. Adherens junctions (AJs; also called the zonula adherens) are critical for the establishment and maintenance of epithelial layers, such as those lining organ surfaces. AJs mediate adhesion between cells, communicate a signal that neighboring cells are present, and anchor the actin cytoskeleton. In serving these roles, AJs regulate normal cell growth and behavior. At several stages of embryogenesis, wound healing, and tumor cell metastasis, cells form and leave epithelia. This process, which involves the disruption and reestablishment of epithelial cell-cell contacts, may be regulated by the disassembly and assembly of AJs. AJs may also function in the transmission of the contact inhibition' signal, which instructs cells to stop dividing once an epithelial sheet is complete. (from OMIM)" @default.
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