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Matches in Ubergraph for { <http://purl.obolibrary.org/obo/NCIT_C17515> ?p ?o ?g. }

• NCIT_C17515 IAO_0000115 "E3 ubiquitin-protein ligase Mdm2 (491 aa, ~55 kDa) is encoded by the human MDM2 gene. This protein is involved in the mediation of the ubiquitination and degradation of protein substrates, and the inhibition of apoptosis induction that is mediated by cellular tumor antigen p53." @default.
• NCIT_C17515 NCIT_NHC0 "C17515" @default.
• NCIT_C17515 NCIT_P100 "164785" @default.
• NCIT_C17515 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
• NCIT_C17515 NCIT_P106 "Enzyme" @default.
• NCIT_C17515 NCIT_P107 "E3 Ubiquitin-Protein Ligase MDM2" @default.
• NCIT_C17515 NCIT_P108 "E3 Ubiquitin-Protein Ligase MDM2" @default.
• NCIT_C17515 NCIT_P207 "C0971008" @default.
• NCIT_C17515 NCIT_P322 "CTRP" @default.
• NCIT_C17515 NCIT_P366 "MDM2_Protein" @default.
• NCIT_C17515 NCIT_P93 "Q00987" @default.
• NCIT_C17515 NCIT_P98 "Inhibits p53 trans-activation, cell cycle arrest, and apoptosis. MDM2 binds p53 in the cell cycle at S/G2M phase and targets p53 for proteasome-mediated proteolysis. MDM2 also inhibits Rb protein and binds p14(ARF), ribosomal protein L5, and specifically to RNA. MDM2 gene expression is induced by DNA damage and regulated by the Ras-MAP kinase pathway. Some soft tissue sarcomas carry amplified MDM2 and overexpress MDM2 protein. (from SWISS-PROT Q00987, OMIM 164785, and NCI)" @default.
• NCIT_C17515 NCIT_R131 NCIT_C17132 @default.
• NCIT_C17515 NCIT_R131 NCIT_C18611 @default.
• NCIT_C17515 NCIT_R131 NCIT_C19779 @default.
• NCIT_C17515 NCIT_R131 NCIT_C20633 @default.
• NCIT_C17515 NCIT_R131 NCIT_C38794 @default.
• NCIT_C17515 NCIT_R131 NCIT_C38881 @default.
• NCIT_C17515 NCIT_R131 NCIT_C38992 @default.
• NCIT_C17515 NCIT_R131 NCIT_C38996 @default.
• NCIT_C17515 NCIT_R131 NCIT_C39040 @default.
• NCIT_C17515 NCIT_R131 NCIT_C39088 @default.
• NCIT_C17515 NCIT_R131 NCIT_C39106 @default.
• NCIT_C17515 NCIT_R131 NCIT_C39179 @default.
• NCIT_C17515 NCIT_R131 NCIT_C39180 @default.
• NCIT_C17515 NCIT_R131 NCIT_C39211 @default.
• NCIT_C17515 NCIT_R131 NCIT_C39699 @default.
• NCIT_C17515 NCIT_R131 NCIT_C39700 @default.
• NCIT_C17515 NCIT_R131 NCIT_C39701 @default.
• NCIT_C17515 NCIT_R131 NCIT_C39702 @default.
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• NCIT_C17515 NCIT_R131 NCIT_C39736 @default.
• NCIT_C17515 NCIT_R131 NCIT_C91436 @default.
• NCIT_C17515 NCIT_R131 NCIT_C91458 @default.
• NCIT_C17515 NCIT_R131 NCIT_C91465 @default.
• NCIT_C17515 NCIT_R131 NCIT_C91473 @default.
• NCIT_C17515 NCIT_R131 NCIT_C91477 @default.
• NCIT_C17515 NCIT_R131 NCIT_C91479 @default.
• NCIT_C17515 NCIT_R131 NCIT_C91495 @default.
• NCIT_C17515 NCIT_R131 NCIT_C91517 @default.
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• NCIT_C17515 NCIT_R131 NCIT_C91546 @default.
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• NCIT_C17515 NCIT_R131 NCIT_C91571 @default.
• NCIT_C17515 NCIT_R131 NCIT_C91572 @default.
• NCIT_C17515 NCIT_R131 NCIT_C91593 @default.
• NCIT_C17515 NCIT_R131 NCIT_C91601 @default.
• NCIT_C17515 NCIT_R131 NCIT_C91602 @default.
• NCIT_C17515 NCIT_R131 NCIT_C91603 @default.
• NCIT_C17515 NCIT_R131 NCIT_C91659 @default.
• NCIT_C17515 NCIT_R131 NCIT_C91663 @default.
• NCIT_C17515 NCIT_R131 NCIT_C91685 @default.
• NCIT_C17515 NCIT_R50 NCIT_C12219 @default.
• NCIT_C17515 NCIT_R50 NCIT_C13303 @default.
• NCIT_C17515 NCIT_R50 NCIT_C13379 @default.
• NCIT_C17515 NCIT_R50 NCIT_C13671 @default.
• NCIT_C17515 NCIT_R50 NCIT_C14073 @default.
• NCIT_C17515 NCIT_R50 NCIT_C14134 @default.
• NCIT_C17515 NCIT_R50 NCIT_C21599 @default.
• NCIT_C17515 NCIT_R51 NCIT_C21176 @default.
• NCIT_C17515 NCIT_R51 NCIT_C26065 @default.
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• NCIT_C17515 NCIT_R52 NCIT_C17021 @default.
• NCIT_C17515 NCIT_R52 NCIT_C18466 @default.
• NCIT_C17515 NCIT_R52 NCIT_C20027 @default.
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• NCIT_C17515 NCIT_R52 NCIT_C95242 @default.
• NCIT_C17515 NCIT_R53 NCIT_C16397 @default.
• NCIT_C17515 NCIT_R53 NCIT_C17019 @default.
• NCIT_C17515 NCIT_R53 NCIT_C17710 @default.
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• NCIT_C17515 NCIT_R53 NCIT_C18081 @default.
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• NCIT_C17515 NCIT_R53 NCIT_C19358 @default.
• NCIT_C17515 NCIT_R53 NCIT_C19406 @default.
• NCIT_C17515 NCIT_R53 NCIT_C19536 @default.
• NCIT_C17515 NCIT_R53 NCIT_C19598 @default.
• NCIT_C17515 NCIT_R53 NCIT_C19903 @default.
• NCIT_C17515 NCIT_R53 NCIT_C19986 @default.
• NCIT_C17515 NCIT_R53 NCIT_C20480 @default.
• NCIT_C17515 NCIT_R53 NCIT_C20750 @default.
• NCIT_C17515 NCIT_R53 NCIT_C21102 @default.
• NCIT_C17515 NCIT_R53 NCIT_C21198 @default.
• NCIT_C17515 NCIT_R53 NCIT_C21243 @default.
• NCIT_C17515 NCIT_R53 NCIT_C28498 @default.
• NCIT_C17515 NCIT_R53 NCIT_C61559 @default.
• NCIT_C17515 NCIT_R54 NCIT_C133710 @default.
• NCIT_C17515 NCIT_R54 NCIT_C16612 @default.
• NCIT_C17515 NCIT_R54 NCIT_C18345 @default.
• NCIT_C17515 NCIT_R54 NCIT_C21281 @default.
• NCIT_C17515 NCIT_R54 NCIT_C25870 @default.
• NCIT_C17515 normalizedInformationContent "100" @default.
• NCIT_C17515 referenceCount "1" @default.
• NCIT_C17515 hasExactSynonym "Double Minute 2 Protein" @default.
• NCIT_C17515 hasExactSynonym "E3 Ubiquitin-Protein Ligase MDM2" @default.
• NCIT_C17515 hasExactSynonym "EC 2.3.2.27" @default.
• NCIT_C17515 hasExactSynonym "HDM2" @default.
• NCIT_C17515 hasExactSynonym "MDM 2 Protein" @default.
• NCIT_C17515 hasExactSynonym "MDM2 Protein" @default.
• NCIT_C17515 hasExactSynonym "MDM2" @default.

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