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- NCIT_C175229 IAO_0000115 "A combination of two neutralizing human monoclonal antibodies cilgavimab and tixagevimab, that are isolated from convalescent patients with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection, and directed against the spike (S) protein, that can potentially be used for passive immunization against Coronavirus disease 2019 (COVID-19). Upon administration of cilgavimab/tixagevimab, both antibodies specifically target and bind to the SARS-CoV-2 S protein, thereby blocking viral attachment and entry into human cells and may thereby neutralize SARS-CoV-2. This may slow the progression of the disease and accelerate recovery, and may potentially provide temporary protection against infection with SARS-CoV-2. S protein, usually found on the surface of SARS-CoV-2, plays an essential role in the infection pathway of the SARS-CoV-2 virus." @default.
- NCIT_C175229 NCIT_A48 NCIT_C17998 @default.
- NCIT_C175229 NCIT_A48 NCIT_C49487 @default.
- NCIT_C175229 NCIT_A48 NCIT_C49488 @default.
- NCIT_C175229 NCIT_NHC0 "C175229" @default.
- NCIT_C175229 NCIT_P106 "Immunologic Factor" @default.
- NCIT_C175229 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C175229 NCIT_P107 "Cilgavimab/Tixagevimab" @default.
- NCIT_C175229 NCIT_P108 "Cilgavimab/Tixagevimab" @default.
- NCIT_C175229 NCIT_P208 "CL1412606" @default.
- NCIT_C175229 NCIT_P322 "ACC/AHA" @default.
- NCIT_C175229 NCIT_P322 "CTRP" @default.
- NCIT_C175229 NCIT_R124 NCIT_C17710 @default.
- NCIT_C175229 NCIT_R124 NCIT_C17828 @default.
- NCIT_C175229 NCIT_R124 NCIT_C18219 @default.
- NCIT_C175229 NCIT_R124 NCIT_C19986 @default.
- NCIT_C175229 NCIT_R124 NCIT_C40474 @default.
- NCIT_C175229 normalizedInformationContent "100" @default.
- NCIT_C175229 referenceCount "1" @default.
- NCIT_C175229 hasExactSynonym "AZD 7442" @default.
- NCIT_C175229 hasExactSynonym "AZD-7442" @default.
- NCIT_C175229 hasExactSynonym "AZD7442" @default.
- NCIT_C175229 hasExactSynonym "AZD8895 + AZD1061" @default.
- NCIT_C175229 hasExactSynonym "AZD8895/AZD1061" @default.
- NCIT_C175229 hasExactSynonym "Anti-SARS-CoV-2 Spike Protein Monoclonal Antibody AZD7442" @default.
- NCIT_C175229 hasExactSynonym "Cilgavimab/Tixagevimab" @default.
- NCIT_C175229 hasExactSynonym "Evusheld" @default.
- NCIT_C175229 hasExactSynonym "Monoclonal Antibody AZD7442" @default.
- NCIT_C175229 hasExactSynonym "Monoclonal antibodies against SARS-CoV-2: tixagevimab/cilgavimab" @default.
- NCIT_C175229 inSubset NCIT_C116977 @default.
- NCIT_C175229 inSubset NCIT_C116978 @default.
- NCIT_C175229 inSubset NCIT_C173381 @default.
- NCIT_C175229 inSubset NCIT_C173383 @default.
- NCIT_C175229 inSubset NCIT_C191200 @default.
- NCIT_C175229 inSubset NCIT_C191387 @default.
- NCIT_C175229 inSubset NCIT_C191404 @default.
- NCIT_C175229 inSubset NCIT_C191670 @default.
- NCIT_C175229 type Class @default.
- NCIT_C175229 isDefinedBy ncit.owl @default.
- NCIT_C175229 label "Cilgavimab/Tixagevimab" @default.
- NCIT_C175229 subClassOf NCIT_C173741 @default.
- NCIT_C175229 subClassOf NCIT_C175229 @default.
- NCIT_C175229 subClassOf NCIT_C1908 @default.
- NCIT_C175229 subClassOf NCIT_C1909 @default.
- NCIT_C175229 subClassOf NCIT_C20401 @default.
- NCIT_C175229 subClassOf NCIT_C307 @default.
- NCIT_C175229 subClassOf NCIT_C308 @default.