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- NCIT_C17532 IAO_0000115 "Retinoid receptors (RARA, RARB, RARG) require co-regulators to increase selective binding to DNA response elements in target genes and enhance transcriptional activity." @default.
- NCIT_C17532 NCIT_NHC0 "C17532" @default.
- NCIT_C17532 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C17532 NCIT_P106 "Receptor" @default.
- NCIT_C17532 NCIT_P107 "Retinoic Acid Receptor" @default.
- NCIT_C17532 NCIT_P108 "Retinoic Acid Receptor" @default.
- NCIT_C17532 NCIT_P207 "C0140278" @default.
- NCIT_C17532 NCIT_P322 "CTRP" @default.
- NCIT_C17532 NCIT_P366 "Retinoic_Acid_Receptor" @default.
- NCIT_C17532 NCIT_P98 "A protein that binds retinoic acid with high affinity. Binding of ligand to RARs attracts co-activator proteins containing a NR box. NCOR1 and SMRT contain CoRNR box sequences, similar to the NR box, in receptor interaction domains and mediate inhibition of gene transcription by RARs. Sequences flanking the CoRNR box determine receptor specificity. Differential recognition of receptors by co-activators and co-repressors is due to subtle differences between CoRNR and NR boxes. The association of SMRT with receptors is destabilized by ligand, triggering the activation process. (from OMIM 180240 and NCI)" @default.
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- NCIT_C17532 normalizedInformationContent "82.080392758357064" @default.
- NCIT_C17532 referenceCount "15" @default.
- NCIT_C17532 hasExactSynonym "Nuclear Receptor Subfamily 1 Group B" @default.
- NCIT_C17532 hasExactSynonym "RAR" @default.
- NCIT_C17532 hasExactSynonym "Retinoic Acid Receptor" @default.
- NCIT_C17532 hasExactSynonym "Retinoid Receptor" @default.
- NCIT_C17532 inSubset NCIT_C116977 @default.
- NCIT_C17532 inSubset NCIT_C142799 @default.
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- NCIT_C17532 type Class @default.
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- NCIT_C17532 label "Retinoic Acid Receptor" @default.
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