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- NCIT_C175526 IAO_0000115 "An extract derived from the Muscadine grape (Vitis rotundifolia), with potential anti-inflammatory, antioxidant, anti-lipidemic and chemopreventive activities. The muscadine grape extract (MGE) contains numerous phytochemicals including hydrolyzable tannins and flavonoids, such as resveratrol, anthocyanin 3,5-diglucosides, quercetin, ellagic acid, myricetin, and kaempferol glycosides. Upon administration, the active components in the MGE scavenge free radicals, protect against oxidation of low-density lipoprotein (LDL), and inhibit cell damage due to reactive oxygen species (ROS). This inhibits oxidative stress and protects against DNA damage. MGE also inhibits enzymes involved in inflammation, cell replication and DNA synthesis, and induces the expression of anti-oxidant enzymes. The active ingredients may also inhibit certain signaling pathways upregulated in some tumor cell types, eventually leading to apoptosis and a reduction in tumor cell proliferation. MGE may also boost energy and prevent fatigue." @default.
- NCIT_C175526 NCIT_A32 NCIT_C1909 @default.
- NCIT_C175526 NCIT_NHC0 "C175526" @default.
- NCIT_C175526 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C175526 NCIT_P107 "Muscadine Grape Extract" @default.
- NCIT_C175526 NCIT_P108 "Muscadine Grape Extract" @default.
- NCIT_C175526 NCIT_P208 "CL1412905" @default.
- NCIT_C175526 NCIT_P322 "CTRP" @default.
- NCIT_C175526 NCIT_P322 "GDC" @default.
- NCIT_C175526 NCIT_P329 "803286" @default.
- NCIT_C175526 NCIT_P330 "803286" @default.
- NCIT_C175526 NCIT_P375 "Muscadine Grape Extract" @default.
- NCIT_C175526 NCIT_P399 "803286" @default.
- NCIT_C175526 normalizedInformationContent "100" @default.
- NCIT_C175526 referenceCount "1" @default.
- NCIT_C175526 hasExactSynonym "MGE" @default.
- NCIT_C175526 hasExactSynonym "Muscadine Grape Extract" @default.
- NCIT_C175526 inSubset NCIT_C116977 @default.
- NCIT_C175526 inSubset NCIT_C116978 @default.
- NCIT_C175526 inSubset NCIT_C128784 @default.
- NCIT_C175526 inSubset NCIT_C157711 @default.
- NCIT_C175526 inSubset NCIT_C157712 @default.
- NCIT_C175526 inSubset NCIT_C176424 @default.
- NCIT_C175526 inSubset NCIT_C177537 @default.
- NCIT_C175526 type Class @default.
- NCIT_C175526 isDefinedBy ncit.owl @default.
- NCIT_C175526 label "Muscadine Grape Extract" @default.
- NCIT_C175526 subClassOf NCIT_C175526 @default.
- NCIT_C175526 subClassOf NCIT_C1908 @default.
- NCIT_C175526 subClassOf NCIT_C1909 @default.
- NCIT_C175526 subClassOf NCIT_C26170 @default.
- NCIT_C175526 subClassOf NCIT_C275 @default.