Matches in Ubergraph for { <http://purl.obolibrary.org/obo/NCIT_C175560> ?p ?o ?g. }
Showing items 1 to 19 of
19
with 100 items per page.
- NCIT_C175560 IAO_0000115 "A fixed combination of praziquantel and pyrantel pamoate, with anthelminthic activity. Upon administration, praziquantel increases the permeability of the tegument of susceptible worms, resulting in an influx and increase in intra-tegumental calcium leading to rapid contractions and paralysis of the worm's musculature. In addition, vacuolization of the tegumental syncytium and blebbing results in tegument disintegration, leads to antigen exposure and elicit host defense responses to the worm. This results in granulomas formation and phagocytosis. Pyrantel pamoate acts as a depolarizing neuromuscular blocking agent resulting in spastic paralysis of the helminths. The parasites are then eliminated through intestinal tract peristalsis of the host." @default.
- NCIT_C175560 NCIT_NHC0 "C175560" @default.
- NCIT_C175560 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C175560 NCIT_P108 "Praziquantel/Pyrantel Pamoate" @default.
- NCIT_C175560 NCIT_P208 "CL1413019" @default.
- NCIT_C175560 normalizedInformationContent "100" @default.
- NCIT_C175560 referenceCount "1" @default.
- NCIT_C175560 hasExactSynonym "Drontal" @default.
- NCIT_C175560 hasExactSynonym "Praziquantel/Pyrantel Pamoate" @default.
- NCIT_C175560 hasExactSynonym "Pyrantel Pamoate/Praziquantel" @default.
- NCIT_C175560 type Class @default.
- NCIT_C175560 isDefinedBy ncit.owl @default.
- NCIT_C175560 label "Praziquantel/Pyrantel Pamoate" @default.
- NCIT_C175560 subClassOf NCIT_C175560 @default.
- NCIT_C175560 subClassOf NCIT_C1908 @default.
- NCIT_C175560 subClassOf NCIT_C1909 @default.
- NCIT_C175560 subClassOf NCIT_C250 @default.
- NCIT_C175560 subClassOf NCIT_C254 @default.
- NCIT_C175560 subClassOf NCIT_C276 @default.