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- NCIT_C175659 IAO_0000115 "A preparation of autologous T-lymphocytes that have been genetically engineered to express a T-cell receptor (TCR) specific for the tumor-associated antigen (TAA) human mesothelin (TMSLN), with potential immunomodulating and antineoplastic activities. Upon administration, the autologous anti-mesothelin TCR-expressing T-cells FH-TCR TMSLN specifically target and bind to mesothelin-expressing tumor cells. This leads to T-cell activation and T-cell mediated lysis of mesothelin-expressing tumor cells. Mesothelin, a cell surface glycoprotein involved in cell adhesion, is overexpressed in a variety of cancer cell types." @default.
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- NCIT_C175659 NCIT_P107 "Autologous Anti-mesothelin TCR-expressing T-cells FH-TCR TMSLN" @default.
- NCIT_C175659 NCIT_P108 "Autologous Anti-mesothelin TCR-expressing T-cells FH-TCR TMSLN" @default.
- NCIT_C175659 NCIT_P208 "CL1412970" @default.
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- NCIT_C175659 hasExactSynonym "Autologous Anti-mesothelin TCR-expressing T-cells FH-TCR TMSLN" @default.
- NCIT_C175659 hasExactSynonym "Autologous Mesothelin-specific TCR T-cells FH-TCR TMSLN" @default.
- NCIT_C175659 hasExactSynonym "Autologous Mesothelin-specific TCR-expressing T-cells FH-TCR TMSLN" @default.
- NCIT_C175659 hasExactSynonym "Autologous Transgenic T-cells Expressing Mesothelin-specific T-cell Receptor FH-TCR TMSLN" @default.
- NCIT_C175659 hasExactSynonym "FH-TCR TMSLN" @default.
- NCIT_C175659 inSubset NCIT_C116977 @default.
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- NCIT_C175659 type Class @default.
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- NCIT_C175659 label "Autologous Anti-mesothelin TCR-expressing T-cells FH-TCR TMSLN" @default.
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