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- NCIT_C175977 IAO_0000115 "A preparation of human T-lymphocytes engineered to express chimeric antigen receptors (CARs) specific for the tumor-associated antigens (TAAs) cluster of differentiation 20 (CD20) and CD22, with potential immunostimulating and antineoplastic activities. Upon administration, the anti-CD20/anti-CD22 CAR T-cells target and bind to both CD20 and CD22 expressed on the surface of tumor cells. This induces selective toxicity in tumor cells expressing these TAAs. CD20 and CD22 are overexpressed in certain hematologic malignancies." @default.
- NCIT_C175977 NCIT_NHC0 "C175977" @default.
- NCIT_C175977 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C175977 NCIT_P108 "Anti-CD20/Anti-CD22 CAR T-cells" @default.
- NCIT_C175977 NCIT_P208 "CL1413417" @default.
- NCIT_C175977 NCIT_P322 "GDC" @default.
- NCIT_C175977 NCIT_P329 "803207" @default.
- NCIT_C175977 NCIT_P330 "803207" @default.
- NCIT_C175977 NCIT_P399 "803207" @default.
- NCIT_C175977 normalizedInformationContent "100" @default.
- NCIT_C175977 referenceCount "1" @default.
- NCIT_C175977 hasExactSynonym "Anti-CD20/Anti-CD22 CAR T-cells" @default.
- NCIT_C175977 hasExactSynonym "CD20/CD22 Dual Targeted CAR T-cells" @default.
- NCIT_C175977 hasExactSynonym "CD20/CD22-targeted CAR T-cells" @default.
- NCIT_C175977 inSubset NCIT_C157711 @default.
- NCIT_C175977 inSubset NCIT_C157712 @default.
- NCIT_C175977 inSubset NCIT_C176424 @default.
- NCIT_C175977 type Class @default.
- NCIT_C175977 isDefinedBy ncit.owl @default.
- NCIT_C175977 label "Anti-CD20/Anti-CD22 CAR T-cells" @default.
- NCIT_C175977 subClassOf NCIT_C129820 @default.
- NCIT_C175977 subClassOf NCIT_C129821 @default.
- NCIT_C175977 subClassOf NCIT_C129826 @default.
- NCIT_C175977 subClassOf NCIT_C137999 @default.
- NCIT_C175977 subClassOf NCIT_C142078 @default.
- NCIT_C175977 subClassOf NCIT_C154231 @default.
- NCIT_C175977 subClassOf NCIT_C175977 @default.
- NCIT_C175977 subClassOf NCIT_C1908 @default.
- NCIT_C175977 subClassOf NCIT_C1909 @default.
- NCIT_C175977 subClassOf NCIT_C1962 @default.
- NCIT_C175977 subClassOf NCIT_C201173 @default.
- NCIT_C175977 subClassOf NCIT_C201174 @default.
- NCIT_C175977 subClassOf NCIT_C274 @default.
- NCIT_C175977 subClassOf NCIT_C307 @default.
- NCIT_C175977 subClassOf NCIT_C308 @default.