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- NCIT_C176055 IAO_0000115 "A coronavirus vaccine composed of a genetically engineered, replication-incompetent, adenovirus serotype 26 (Ad26) vector expressing the stabilized pre-fusion spike (S) protein of the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), with potential immunomodulating and anti-COVID-19 activities. Upon intramuscular administration of the COVID-19 vaccine Ad26.COV2.S, the Ad26 infects human cells, which produces SARS-CoV-2 S protein. The released S protein activates the immune system to induce a humoral and cell-mediated immune response against SARS-CoV-2. This may prevent SARS-CoV-2 infection and inhibit viral replication. S protein, usually found on the surface of SARS-CoV-2, plays an essential role in the infection pathway of the SARS-CoV-2 virus." @default.
- NCIT_C176055 NCIT_NHC0 "C176055" @default.
- NCIT_C176055 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C176055 NCIT_P107 "COVID-19 Vaccine Ad26.COV2.S" @default.
- NCIT_C176055 NCIT_P108 "COVID-19 Vaccine Ad26.COV2.S" @default.
- NCIT_C176055 NCIT_P208 "CL1651091" @default.
- NCIT_C176055 NCIT_P319 "JT2NS6183B" @default.
- NCIT_C176055 NCIT_P322 "ACC/AHA" @default.
- NCIT_C176055 NCIT_P322 "CTRP" @default.
- NCIT_C176055 NCIT_P322 "FDA" @default.
- NCIT_C176055 NCIT_P322 "SeroNet" @default.
- NCIT_C176055 NCIT_P399 "813348" @default.
- NCIT_C176055 normalizedInformationContent "100" @default.
- NCIT_C176055 referenceCount "1" @default.
- NCIT_C176055 hasExactSynonym "AD26.COV2.S" @default.
- NCIT_C176055 hasExactSynonym "Ad26-encoding SARS-CoV-2 Spike Protein Vaccine" @default.
- NCIT_C176055 hasExactSynonym "Ad26.COV2.S (Johnson & Johnson/Janssen)" @default.
- NCIT_C176055 hasExactSynonym "Ad26.COV2.S" @default.
- NCIT_C176055 hasExactSynonym "Ad26COVS1" @default.
- NCIT_C176055 hasExactSynonym "COVID-19 Vaccine Ad26.COV2.S" @default.
- NCIT_C176055 hasExactSynonym "JNJ 78436735" @default.
- NCIT_C176055 hasExactSynonym "JNJ-78436735" @default.
- NCIT_C176055 hasExactSynonym "JNJ78436735" @default.
- NCIT_C176055 hasExactSynonym "Johnson & Johnson COVID-19 Vaccine" @default.
- NCIT_C176055 hasExactSynonym "Johnson and Johnson COVID-19 Vaccine" @default.
- NCIT_C176055 inSubset NCIT_C116977 @default.
- NCIT_C176055 inSubset NCIT_C116978 @default.
- NCIT_C176055 inSubset NCIT_C173381 @default.
- NCIT_C176055 inSubset NCIT_C173383 @default.
- NCIT_C176055 inSubset NCIT_C179027 @default.
- NCIT_C176055 inSubset NCIT_C189083 @default.
- NCIT_C176055 inSubset NCIT_C191200 @default.
- NCIT_C176055 inSubset NCIT_C191387 @default.
- NCIT_C176055 inSubset NCIT_C191404 @default.
- NCIT_C176055 inSubset NCIT_C191671 @default.
- NCIT_C176055 inSubset NCIT_C63923 @default.
- NCIT_C176055 type Class @default.
- NCIT_C176055 isDefinedBy ncit.owl @default.
- NCIT_C176055 label "COVID-19 Vaccine Ad26.COV2.S" @default.
- NCIT_C176055 subClassOf NCIT_C173023 @default.
- NCIT_C176055 subClassOf NCIT_C176055 @default.
- NCIT_C176055 subClassOf NCIT_C1908 @default.
- NCIT_C176055 subClassOf NCIT_C1909 @default.
- NCIT_C176055 subClassOf NCIT_C307 @default.
- NCIT_C176055 subClassOf NCIT_C308 @default.
- NCIT_C176055 subClassOf NCIT_C923 @default.