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- NCIT_C176568 IAO_0000115 "A preparation of autologous human T-lymphocytes that are genetically engineered to express a chimeric antigen receptor (CAR) targeting the tumor-associated antigen (TAA) CD22, with potential immunostimulating and antineoplastic activities. Upon administration, the autologous anti-CD22 CAR-expressing T-cells SCRI-CAR22v2 express anti-CD22-CAR on their cell surfaces and bind to the CD22 antigen on tumor cell surfaces leading to lysis of CD22-expressing B-cells. CD22, a B-lineage-restricted, transmembrane phosphoglycoprotein, is expressed on malignant B-cells." @default.
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- NCIT_C176568 NCIT_P107 "Autologous Anti-CD22 CAR-expressing T-cells SCRI-CAR22v2" @default.
- NCIT_C176568 NCIT_P108 "Autologous Anti-CD22 CAR-expressing T-cells SCRI-CAR22v2" @default.
- NCIT_C176568 NCIT_P208 "CL1642402" @default.
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- NCIT_C176568 hasExactSynonym "Autologous Anti-CD22 CAR-T Cells SCRI-CAR22v2" @default.
- NCIT_C176568 hasExactSynonym "Autologous Anti-CD22 CAR-expressing T-cells SCRI-CAR22v2" @default.
- NCIT_C176568 hasExactSynonym "Autologous CD22-CAR-expressing T Lymphocytes SCRI-CAR22v2" @default.
- NCIT_C176568 hasExactSynonym "SCRI CAR22v2" @default.
- NCIT_C176568 hasExactSynonym "SCRI-CAR22v2" @default.
- NCIT_C176568 hasExactSynonym "SCRICAR22v2" @default.
- NCIT_C176568 inSubset NCIT_C116977 @default.
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- NCIT_C176568 type Class @default.
- NCIT_C176568 isDefinedBy ncit.owl @default.
- NCIT_C176568 label "Autologous Anti-CD22 CAR-expressing T-cells SCRI-CAR22v2" @default.
- NCIT_C176568 subClassOf NCIT_C129820 @default.
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- NCIT_C176568 subClassOf NCIT_C308 @default.