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- NCIT_C176779 IAO_0000115 "An orally bioavailable gelatin capsule-based formulation containing tempol, a hydrophilic piperidine nitroxide, with potential chemo/radioprotective and antioxidant activities. Upon oral administration of MBM-02, tempol, being a free radical compound, may be able to protect cells against the damaging effects of reactive oxygen species (ROS), upon exposure to ionizing radiation and oxidative stress. MBM-02 may selectively protect normal tissue from chemotherapy- and radiation-induced toxicities. Tempol is in its protective form in oxygenated cells and is in its unprotective form in the hypoxic tumor microenvironment (TME)." @default.
- NCIT_C176779 NCIT_NHC0 "C176779" @default.
- NCIT_C176779 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C176779 NCIT_P108 "Tempol-containing MBM-02" @default.
- NCIT_C176779 NCIT_P208 "CL1642556" @default.
- NCIT_C176779 NCIT_P329 "803752" @default.
- NCIT_C176779 NCIT_P330 "803752" @default.
- NCIT_C176779 NCIT_P399 "803752" @default.
- NCIT_C176779 normalizedInformationContent "100" @default.
- NCIT_C176779 referenceCount "1" @default.
- NCIT_C176779 hasExactSynonym "MBM 02" @default.
- NCIT_C176779 hasExactSynonym "MBM-02" @default.
- NCIT_C176779 hasExactSynonym "MBM02" @default.
- NCIT_C176779 hasExactSynonym "Tempol-containing MBM-02" @default.
- NCIT_C176779 inSubset NCIT_C176424 @default.
- NCIT_C176779 type Class @default.
- NCIT_C176779 isDefinedBy ncit.owl @default.
- NCIT_C176779 label "Tempol-containing MBM-02" @default.
- NCIT_C176779 subClassOf NCIT_C176779 @default.
- NCIT_C176779 subClassOf NCIT_C1908 @default.
- NCIT_C176779 subClassOf NCIT_C1909 @default.
- NCIT_C176779 subClassOf NCIT_C2459 @default.
- NCIT_C176779 subClassOf NCIT_C26170 @default.
- NCIT_C176779 subClassOf NCIT_C275 @default.
- NCIT_C176779 subClassOf NCIT_C797 @default.