Matches in Ubergraph for { <http://purl.obolibrary.org/obo/NCIT_C177069> ?p ?o ?g. }
Showing items 1 to 30 of
30
with 100 items per page.
- NCIT_C177069 IAO_0000115 "An orally bioavailable toll-like receptor type 7 and 8 (TLR 7/8) dual antagonist, with potential anti-inflammatory and immunomodulating activities. Upon oral administration, enpatoran binds to and inhibits the activity of TLR7 and 8, thereby inhibiting TLR7/8-mediated pathways. This may inhibit the production of pro-inflammatory cytokines, and block the activation of immune responses. TLR7 and 8, members of the TLR family, play fundamental roles in the activation of the innate immune system, myeloid cell responses and tumor antigen presentation." @default.
- NCIT_C177069 NCIT_A7 NCIT_C30108 @default.
- NCIT_C177069 NCIT_A7 NCIT_C30109 @default.
- NCIT_C177069 NCIT_NHC0 "C177069" @default.
- NCIT_C177069 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C177069 NCIT_P108 "Enpatoran" @default.
- NCIT_C177069 NCIT_P208 "CL1642847" @default.
- NCIT_C177069 NCIT_P210 "2101938-42-3" @default.
- NCIT_C177069 NCIT_P319 "7CZ390V26X" @default.
- NCIT_C177069 NCIT_P322 "FDA" @default.
- NCIT_C177069 normalizedInformationContent "100" @default.
- NCIT_C177069 referenceCount "1" @default.
- NCIT_C177069 hasExactSynonym "ENPATORAN" @default.
- NCIT_C177069 hasExactSynonym "Enpatoran" @default.
- NCIT_C177069 hasExactSynonym "M 5049" @default.
- NCIT_C177069 hasExactSynonym "M-5049" @default.
- NCIT_C177069 hasExactSynonym "M5049" @default.
- NCIT_C177069 hasExactSynonym "TLR 7/8 Antagonist M5049" @default.
- NCIT_C177069 hasExactSynonym "TLR 7/8 Inhibitor M5049" @default.
- NCIT_C177069 inSubset NCIT_C173381 @default.
- NCIT_C177069 inSubset NCIT_C173383 @default.
- NCIT_C177069 inSubset NCIT_C63923 @default.
- NCIT_C177069 type Class @default.
- NCIT_C177069 isDefinedBy ncit.owl @default.
- NCIT_C177069 label "Enpatoran" @default.
- NCIT_C177069 subClassOf NCIT_C177069 @default.
- NCIT_C177069 subClassOf NCIT_C1908 @default.
- NCIT_C177069 subClassOf NCIT_C1909 @default.
- NCIT_C177069 subClassOf NCIT_C308 @default.
- NCIT_C177069 subClassOf NCIT_C574 @default.