Matches in Ubergraph for { <http://purl.obolibrary.org/obo/NCIT_C177085> ?p ?o ?g. }
Showing items 1 to 34 of
34
with 100 items per page.
- NCIT_C177085 IAO_0000115 "A formulation consisting of lipid nanoparticle (LNP) encapsulating a nucleoside modified messenger RNA (modRNA) encoding an optimized form of the full-length severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) spike glycoprotein (SP), with potential immunizing and anti-COVID-19 activities. Upon injection of ganulameran, the LNPs bind to the plasma membrane of nearby cells and release SARS-CoV-2 SP mRNA into the cell. The mRNA is then translated by the cellular protein translation machinery to produce SARS-CoV-2 SP. This may stimulate the immune system to induce an antibody and T-cell-mediated immune response. This may provide active immunization against SARS-CoV-2 infection. SP, usually found on the surface of SARS-CoV-2, plays an essential role in the infection pathway of the SARS-CoV-2 virus." @default.
- NCIT_C177085 NCIT_NHC0 "C177085" @default.
- NCIT_C177085 NCIT_P106 "Nucleic Acid, Nucleoside, or Nucleotide" @default.
- NCIT_C177085 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C177085 NCIT_P108 "Ganulameran" @default.
- NCIT_C177085 NCIT_P208 "CL1642807" @default.
- NCIT_C177085 NCIT_P210 "2433844-55-2" @default.
- NCIT_C177085 NCIT_P319 "I74C16KK3J" @default.
- NCIT_C177085 NCIT_P322 "FDA" @default.
- NCIT_C177085 normalizedInformationContent "100" @default.
- NCIT_C177085 referenceCount "1" @default.
- NCIT_C177085 hasExactSynonym "BNT 162b3" @default.
- NCIT_C177085 hasExactSynonym "BNT-162b3" @default.
- NCIT_C177085 hasExactSynonym "BNT162b3 COVID-19 Vaccine" @default.
- NCIT_C177085 hasExactSynonym "BNT162b3 SARS-CoV-2 Vaccine" @default.
- NCIT_C177085 hasExactSynonym "BNT162b3" @default.
- NCIT_C177085 hasExactSynonym "GANULAMERAN" @default.
- NCIT_C177085 hasExactSynonym "Ganulameran" @default.
- NCIT_C177085 inSubset NCIT_C173381 @default.
- NCIT_C177085 inSubset NCIT_C173383 @default.
- NCIT_C177085 inSubset NCIT_C63923 @default.
- NCIT_C177085 type Class @default.
- NCIT_C177085 isDefinedBy ncit.owl @default.
- NCIT_C177085 label "Ganulameran" @default.
- NCIT_C177085 subClassOf NCIT_C172787 @default.
- NCIT_C177085 subClassOf NCIT_C173020 @default.
- NCIT_C177085 subClassOf NCIT_C173023 @default.
- NCIT_C177085 subClassOf NCIT_C177085 @default.
- NCIT_C177085 subClassOf NCIT_C181140 @default.
- NCIT_C177085 subClassOf NCIT_C1908 @default.
- NCIT_C177085 subClassOf NCIT_C1909 @default.
- NCIT_C177085 subClassOf NCIT_C307 @default.
- NCIT_C177085 subClassOf NCIT_C308 @default.
- NCIT_C177085 subClassOf NCIT_C923 @default.