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- NCIT_C177439 IAO_0000115 "A synthetic double-stranded RNA (dsRNA) polyinosinic:polycytidylic acid (poly I:C) nanoplexed with the cationic carrier polyethylenimine (PEI), with potential immunostimulating and antineoplastic activities. Upon intratumoral administration, nanoplexed poly I:C BO-112, which mimics viral RNAs, may stimulate the release of cytotoxic cytokines and induces interferon-gamma production. This may increase the tumoricidal activities of various immunohematopoietic cells. The PEI carrier enhances the delivery of the agent into the cells." @default.
- NCIT_C177439 NCIT_NHC0 "C177439" @default.
- NCIT_C177439 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C177439 NCIT_P107 "Nanoplexed Poly I:C BO-112" @default.
- NCIT_C177439 NCIT_P108 "Nanoplexed Poly I:C BO-112" @default.
- NCIT_C177439 NCIT_P208 "CL1643313" @default.
- NCIT_C177439 NCIT_P322 "CTRP" @default.
- NCIT_C177439 NCIT_P322 "GDC" @default.
- NCIT_C177439 NCIT_P329 "783997" @default.
- NCIT_C177439 NCIT_P330 "783997" @default.
- NCIT_C177439 NCIT_P399 "783997" @default.
- NCIT_C177439 normalizedInformationContent "100" @default.
- NCIT_C177439 referenceCount "1" @default.
- NCIT_C177439 hasExactSynonym "BO 112" @default.
- NCIT_C177439 hasExactSynonym "BO-112" @default.
- NCIT_C177439 hasExactSynonym "BO112" @default.
- NCIT_C177439 hasExactSynonym "Nanoplexed Poly I:C BO-112" @default.
- NCIT_C177439 hasExactSynonym "Nanoplexed Poly IC BO-112" @default.
- NCIT_C177439 hasExactSynonym "Nanoplexed Polyinosinic:Polycytidylic Acid BO-112" @default.
- NCIT_C177439 inSubset NCIT_C116977 @default.
- NCIT_C177439 inSubset NCIT_C116978 @default.
- NCIT_C177439 inSubset NCIT_C128784 @default.
- NCIT_C177439 inSubset NCIT_C157711 @default.
- NCIT_C177439 inSubset NCIT_C157712 @default.
- NCIT_C177439 inSubset NCIT_C176424 @default.
- NCIT_C177439 type Class @default.
- NCIT_C177439 isDefinedBy ncit.owl @default.
- NCIT_C177439 label "Nanoplexed Poly I:C BO-112" @default.
- NCIT_C177439 subClassOf NCIT_C177439 @default.
- NCIT_C177439 subClassOf NCIT_C1908 @default.
- NCIT_C177439 subClassOf NCIT_C1909 @default.
- NCIT_C177439 subClassOf NCIT_C2139 @default.
- NCIT_C177439 subClassOf NCIT_C308 @default.